Results 191 to 200 of about 71,097 (291)

Hepatic transcriptomic alterations for N,N-dimethyl-p-toluidine (DMPT) and p-toluidine after 5-day exposure in rats

open access: yesArchives of Toxicology, 2017
J. Dunnick   +8 more
semanticscholar   +1 more source

Presenilin L166P Mutation, a Model of Familial Alzheimer's Disease, Leads to Early Onset Bone Loss

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
Female‐specific bone loss in Alzheimer's disease mouse models: There is a significant alteration of bone phenotype during Alzheimer's disease. Using integrated imaging and biological assays, we observed changes in the bone microarchitecture, composition, and function in PSEN K1 and PSEN1/hAPP Tg+ mice, predominantly in the females. ABSTRACT Accelerated
Vidyani Suryadevara   +12 more
wiley   +1 more source

Vildagliptin and Omarigliptin Differentially Bind to DPP‐4 Homodimers and Modulate Osteoclast‐Mediated Bone Resorption

open access: yesComprehensive Physiology, Volume 16, Issue 1, February 2026.
Vildagliptin and omarigliptin, dipeptidyl peptidase‐4 (DPP‐4) inhibitors, have differential effects on bone cells. Although vildagliptin improved the bone microstructure of high‐fat diet‐fed rats, it was unable to downregulate osteoclastogenesis or the expression of key osteoclast transcripts.
Ratchaneevan Aeimlapa   +11 more
wiley   +1 more source

The Healing Effect of Aged Garlic Extract on Acetic Acid and 5-Fluorouracil-Induced Oral Mucositis in Mice. [PDF]

open access: yesJ Clin Med Res
Kawasaki K   +6 more
europepmc   +1 more source

Astrocyte MCT1 Expression Does Not Contribute to the Axonal Degenerative Phenotype Observed With Ubiquitous MCT1 Depletion

open access: yesGlia, Volume 74, Issue 2, February 2026.
Loss of astrocytic MCT1 does not cause late onset neurodegeneration. As ubiquitous MCT1 deletion causes axonal degeneration, oligodendrocytes and potentially other cells are more prominent drivers of MCT1‐mediated metabolic support of neurons. ABSTRACT We recently reported that the loss of oligodendrocyte metabolic support through the lactate and ...
Thomas Philips   +9 more
wiley   +1 more source

Aberrant Molecular Myelin Architecture in Charcot–Marie–Tooth Disease Type 1A and Hereditary Neuropathy With Liability to Pressure Palsies

open access: yesGlia, Volume 74, Issue 2, February 2026.
PMP22 copy number variation disrupts myelin architecture at SLIs and Nodes of Ranvier. Adherens junction and axoglial domain defects are often more severe in CMT1A than HNPP. Findings support PMP22 functioning as a structural organizer of myelin. ABSTRACT Charcot–Marie–Tooth Disease Type 1A (CMT1A) and Hereditary Neuropathy with Liability to Pressure ...
Kathryn R. Moss   +3 more
wiley   +1 more source

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