Results 231 to 240 of about 71,097 (291)

Nanoplastics trigger glial–neuronal collagen signaling miscommunication to exacerbate cognitive impairment in Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 1, January 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) is a progressive neurodegenerative disorder with limited treatments and poorly defined environmental risks. Micro‐ and nanoplastics (MNPs) are widespread pollutants linked to neurotoxicity, but their role in AD remains unclear.
Yizhou Zhong   +20 more
wiley   +1 more source

Machine Learning Integration Framework Constructs a Lactylation‐Associated Gene Signature to Improve Prognosis in Bladder Cancer

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Bladder cancer remains a significant challenge in oncology owing to its high recurrence rates and limited treatment options, particularly in cases of resistance to standard therapies. Aims Our study aimed to pinpoint a lactylation‐associated gene signature capable of predicting prognosis and providing important theoretical support ...
Jingsong Wang   +8 more
wiley   +1 more source

Antiurolithiatic Potential of a Series of Phthalimide Derivatives on Calcium Oxalate Crystals

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT Urolithiasis, primarily caused by calcium oxalate crystals, represents a major health concern due to high recurrence rates and limitations of current treatments in dissolving existing stones. This study investigated the antiurolithiatic potential of 15 phthalimide derivatives against calcium oxalate monohydrate (COM) and dihydrate (COD ...
Daniele Regina Sonza   +7 more
wiley   +1 more source

9‐Deoxymuzigadial, a Sesquiterpene Isolated From Drimys brasiliensis (Winteraceae), Displays Reduced Cytotoxicity In Vitro and Modulates Leukocyte Activity and Fibrogenesis In Vivo

open access: yesChemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT The aims of this study were to investigate in vitro cytotoxic potential and the effects of daily administration during the inflammatory response induced by sponge implants in mice of the sesquiterpene 9‐deoxymuzigadial (9‐DOM), isolated from Drimys brasiliensis (Winteraceae).
Bruno Antonio Ferreira   +7 more
wiley   +1 more source

Impact of Photoactivated Disinfection on Dentin Permeability and Bacterial Eradication.

open access: yesJ Pharm Bioallied Sci
Arya A   +5 more
europepmc   +1 more source

MAFG Induces the Methylation of CRYAB to Promote the Activation of A1 Astrocyte After Spinal Cord Injury

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
All in all, silencing MAFG inhibited the activation of A1 astrocyte and neuroinflammation through regulating CRYAB methylation. ABSTRACT Purpose To investigate the effects of MAF bZIP transcription factor G (MAFG) on the transformation of A1/A2 reactive astrocytes and the production of inflammatory factors after spinal cord injury (SCI). Methods An SCI
Xuefei Li   +5 more
wiley   +1 more source

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