Results 41 to 50 of about 53,165 (288)

Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1

Advanced Science, EarlyView.
The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo, Yuanyuan Li, Wensheng Li, Tongrui Wu, Yi Liu, Yacoubou Abdoul Razak Mahaman, Jianzhi Wang, Rong Liu, Wei Liu, Hui Shen, Xiaochuan Wang   +10 more
wiley   +1 more source

Preparation and characterization of new and novel Poly-o-Toluidine Sn(II) silicotungstate ternary nanocomposite and its environment application as indicator electrode

Journal of Saudi Chemical Society, 2021
Advanced poly(O-Toluidine) Sn(II) silicotungstate (POTSn(II)SiO2WO3) ternary nanocomposite synthesized by the extremely well-known simple sol–gel method. We have selected a low-cost o-toluidine monomer initiator and abundantly available metal of divalent
Anish Khan, Imran Khan, Abdullah M. Asiri   +2 more
doaj  

Identification of Schwann Cells in Human Intracranial Arteries: Potential Regulatory Role in Atherosclerotic Plaque Progression

Advanced Science, EarlyView.
Schwann cells may facilitate intracranial plaque progression via neurovascular remodelingcting with vascular smooth muscle cells in atherosclerotic plaques, with the SPP1 ‐ ITGB1 signaling axis mediating this interaction as a novel mechanism. Abstract Intracranial atherosclerosis (ICAS), a common cause of ischemic stroke, remains a therapeutic ...
Zijue Wang, Yangzhige He, Weizhuang Yuan, Yijun Xia, Manqiu Ding, Zhen Chen, Naili Wang, Chao Ma, Xiaoyue Wang, Yan Xu, Weihai Xu   +10 more
wiley   +1 more source

Mechanochemistry‐Driven Borrowing Hydrogen Processes for Ru‐Catalyzed N‐Alkylation: A Pathway to Enhanced Sustainability and Efficiency

Angewandte Chemie, EarlyView.
This work pioneers a solvent‐free mechanochemical borrowing hydrogen (BH) strategy for the rapid and efficient N‐alkylation of amines and heterocycles. By removing harsh conditions and toxic reagents while employing a simple Ru catalyst, this approach redefines BH as a cleaner, more versatile, and sustainable platform for synthetic chemistry.
Sourav Behera, Dipak J. Fartade, Rita Mocci, Michela Matta, Lidia De Luca, Andrea Porcheddu   +5 more
wiley   +2 more sources

Color Changes in Artificially Induced Incipient Caries after Photodynamic Therapy with Different Concentrations of Methylene Blue and Toluidine Blue and Irrigation with Water and Hypochlorite

International Journal of Dentistry
Aim. The aim of this study was to assess the color changes in artificially induced incipient caries after photodynamic therapy (PDT) using different concentrations of methylene blue and toluidine blue, along with irrigation using water and hypochlorite ...
Sedighe Sadat Hashemikamangar, Mohammadreza Khadivi Moghadam, Mahtab Vahedi, Marzieh Rohaninasab, Nasim Chiniforush   +4 more
doaj   +1 more source

Gas Bubbles from Biodegradable Magnesium Implants Convey Mechanical Cues and Promote Immune Cell Stimulation

Advanced Science, EarlyView.
Bubbles in soft tissue are the unavoidable consequence of magnesium implant degradation in patients, yet their biological significance remains unclear. Using advanced imaging and spatial transcriptomics, this study reveals a pronounced inflammatory and mechanical response near bubbles, contrasting with pro‐regenerative events closer to the implant ...
Heithem Ben Amara, Jincy Philip, Omar Omar, Peter Thomsen   +3 more
wiley   +1 more source

Tailoring Tubular Supramolecular Polymers with Polar Lumens to Host Hydrophilic Dye Molecules

Angewandte Chemie, EarlyView.
A unique class of tubular polymer structures that are soluble in apolar organic solvents but are endowed with polar pores has been created through the rational design of the monomer units, which self‐assemble in amphiphilic cyclic entities that then stack into tubular architectures. These tailored assemblies are able to selectively host hydrophilic dye
Irene Sancho‐Casado, Fátima Aparicio, Marina González‐Sánchez, Raquel Chamorro, Víctor Vega‐Mayoral, Juan Cabanillas‐González, David González‐Rodríguez   +6 more
wiley   +2 more sources

Umwandlung des Anilins in Toluidin [PDF]

Berichte der deutschen chemischen Gesellschaft, 1872
n ...
openaire   +3 more sources

Unraveling Tissue‐Specific Fatty Acid Biosynthesis and Inter‐Tissue Crosstalk in Mice through Stable‐Isotope Tracing Metabolomics

Advanced Science, EarlyView.
Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing, Ruohong Wang, Tianzhang Kou, Wenbin Liu, Zheng‐Jiang Zhu   +4 more
wiley   +1 more source

Radical Reactivity of Thioimidates for Diversified Polymeric Amidines with Tunable Properties

Angewandte Chemie, EarlyView.
Thioimidates serve as a synthetic branch point for other functional groups but are relatively unexplored in radical and polymer chemistry. This study marks the first investigation of thioimidate radical chemistry and subsequent elaboration into diverse polymeric amidines.
Selin Kinali‐Demirci, Serkan Demirci, Jacob Byerly‐Duke, Brett VanVeller   +3 more
wiley   +2 more sources