Results 101 to 110 of about 556 (212)

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

Advanced Science, Volume 13, Issue 43, 3 August 2026.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao, Xinyu Wang, Zhifeng Wu, Xinya Zhang, Xiao Geng, Ti Zhang, Yue Wang, Hongwei Xia, Jun Zhang, Xianbo Qiu, Cuiru Sun, Yingjie Yu, Wenli Dai, Hua Tian, Qing Cai   +14 more
wiley   +1 more source

Subtle effects of acetone and amitraz on sucrose sensitivity and recall in honey bees. [PDF]

Sci Rep
Huang EW, Fahrbach SE.
europepmc   +1 more source

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

Advanced Science, Volume 13, Issue 45, 13 August 2026.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng, Jing‐Rong Cheng, Yu Qin, Jie Lei, Chen‐Chen Gao, Hong‐Ying Fu, Li‐Ping Wu, Thanh D. Nguyen, Xu‐Liang Deng, Kai‐Yuan Fu, Yang Liu   +10 more
wiley   +1 more source

Preliminary Analysis of CpG, CHG and CHH Methylation in the Mitochondrial Control Region of Dogs With Malignant Mammary Gland Tumours

Animal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT Canine mammary tumours (CMTs) are one of the most frequently observed malignancies in female dogs. Many studies have investigated epigenetic changes in CMT at the nuclear level, yet the role of mtDNA methylation, particularly in the D‐loop region, remains largely unexplored.
Krzysztof Kowal, Kaja Ziółkowska‐Twarowska, Angelika Tkaczyk‐Wlizło, Carlos Vaamonde‐García, Mercedes Fernández‐Moreno, Brygida Ślaska   +5 more
wiley   +1 more source

Effectiveness of teriflunomide in patients with relapsing multiple sclerosis who switched from other disease-modifying therapies. [PDF]

Medicine (Baltimore)
Berkovich R, Greene N, Reddy SR, Chang E, Tarbox MH, Fadaee S, Quach C, Pyatkevich Y.   +7 more
europepmc   +1 more source

Xstainer: A Novel Virtual Staining Tool Powered by Advanced Deep Learning Techniques

Advanced Intelligent Systems, Volume 8, Issue 8, August 2026.
Xstainer is a deep learning–based virtual staining framework that converts hematoxylin and eosin‐stained whole slide images into multiple histochemical stains, including Masson's trichrome, Periodic acid‐Schiff, Jones methenamine silver, and Toluidine blue.
Fatma Nur Kinali, Derya Demir, Kutsev B. Ozyoruk, Yasin Almalioglu, Emre C. Kose, Drew F. K. Williamson, Gurdeniz Serin, G. Evren Keles, Banu S. Kumbaraci, Ceren Utku, Uguray P. Hacisalihoglu, Ilknur Turkmen, Figen Ozturk, Kayhan Basak, Yavuz Nuri Ertas, Mehmet Turan   +15 more
wiley   +1 more source

Long-term safety and efficacy of ponesimod in participants with relapsing multiple sclerosis: results from the phase 3 OPTIMUM 5-year long term extension study. [PDF]

J Neurol
Montalban X, Hohlfeld R, Pozzilli C, Freedman MS, Sprenger T, Fox RJ, Havrdova EK, Lublin F, Huang D, Raghavan N, Wong J, Vaclavkova A, Dukovski J, Linscheid P, Burcklen M, Kappos L.   +15 more
europepmc   +1 more source

Vorinostat Mitigates Early Brain Injury Following Subarachnoid Hemorrhage Through Modulation of the C3aR1/TGF‐β/Smad Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
C3aR1 mediates microglial activation after SAH in part through the TGF‐β/Smad signaling pathway. Vorinostat alleviates early brain injury after SAH by reducing C3aR1 levels. ABSTRACT Background Excessive microglial activation after subarachnoid hemorrhage (SAH) contributes to early brain injury (EBI) and poor clinical outcomes.
Chonghui Zhang, Yifan Xu, Junshan Wan, Jinpeng Wu, Chao Wang, Yugong Feng   +5 more
wiley   +1 more source

Synergistic Effects of Amitraz and Dinotefuran on Honey Bee Health: Impacts on Survival, Gene Expression, and Hypopharyngeal Gland Morphology. [PDF]

Int J Mol Sci
Esmaeily M, Begna T, Jang H, Kwon S, Jung C.   +4 more
europepmc   +1 more source

Application of Focused Ultrasound for the Treatment of Tendinopathy: An In Vivo Feasibility, Safety, and Efficacy Study

Journal of Orthopaedic Research, Volume 44, Issue 8, August 2026.
ABSTRACT Mechanical loading‐based rehabilitation of tendinopathies improves symptoms and tendon biomechanics, motivating interest in non‐invasive treatment options. Focused ultrasound (FUS) is a promising technology that precisely targets tissue regions, inducing desired bioeffects while minimally affecting surrounding tissues. To explore its potential
Chitra Meduri, Emily P. Rogers, Dylan C. Easley, P. Gunnar Brolinson, Eli Vlaisavljevich, Vincent M. Wang   +5 more
wiley   +1 more source