Results 241 to 250 of about 4,432 (285)

Cold Plasma Generates a Localized Inflammatory Response and Promotes Muscle Repair

open access: yesAdvanced Therapeutics, Volume 8, Issue 7, July 2025.
The immediate tissue response to plasma is a pro‐inflammatory response which is characterized by collagen clumping, innate immune cell infiltration, enhanced metabolic processes, and decreased apoptosis. The long‐term tissue response (4‐ and 14‐days) to plasma treatment is characterized by a decreased inflammatory response, decreased adipogenesis, and ...
Carly J. Smith   +9 more
wiley   +1 more source

Chromatographic activity of residual silanols of alkylsilane derivatized silica surfaces [PDF]

open access: yes
Alex B. Scholten   +38 more
core   +1 more source

Engineered Stem Cell Clusters for Extracellular Vesicles‐Mediated Gene Delivery to Rejuvenate Chondrocytes and Facilitate Chondrogenesis in Osteoarthritis Therapy

open access: yesAdvanced Science, Volume 12, Issue 25, July 3, 2025.
BMSCmotif+miR874/MS system is designed as a gene delivery platform utilizing engineered bone marrow mesenchymal stem cell (BMSC)‐derived extracellular vesicles (EVs) for intercellular communication to achieve sustained delivery of miRNA‐874‐3p. Rejuvenation of chondrocytes and promotion of chondrogenesis are achieved by inhibition of the NF‐κB pathway,
Yuezhou Wu   +7 more
wiley   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

open access: yesAdvanced Science, Volume 12, Issue 25, July 3, 2025.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang   +11 more
wiley   +1 more source

MdDSK2a‐Like‐MdMTA Module Functions in Apple Cold Response via Regulating ROS Detoxification and Cell Wall Deposition

open access: yesAdvanced Science, Volume 12, Issue 26, July 10, 2025.
Under cold stress, MdDSK2a‐like is degraded via the 26S proteasome pathway, thereby alleviating the degradation of MdMTA induced by the 26S proteasome and autophagy pathways mediated by MdDSK2a‐like. The accumulated MdMTA increases the m6A levels of cold‐responsive genes, thereby contributing to increased ROS detoxification, deposition of cell wall, as
Nan Hou   +18 more
wiley   +1 more source

Lateral Thinking: Exploring the Lateral Entorhinal Cortex Projections to the Hippocampus in the Rodent Brain

open access: yesJournal of Comparative Neurology, Volume 533, Issue 7, July 2025.
Localization and layers of the lateral entorhinal cortex. Photomicrographs depicting both coronal (A: 1–4) and sagittal (B: 5–8) sections from a mouse brain to show different perspectives of the entorhinal cortex inputs to the hippocampus (HC). Sections were stained with toluidine blue to aid with the visualization of the six layers of the lateral ...
Rebecca Przy   +4 more
wiley   +1 more source

Headache in Multiple Sclerosis: A Narrative Review. [PDF]

open access: yesMedicina (Kaunas)
Adamczyk B   +8 more
europepmc   +1 more source

Cellular Organization and Migration Pathways of the Ventricular–Subventricular Zone in the Juvenile Swine Brain (Sus scrofa domesticus)

open access: yesJournal of Comparative Neurology, Volume 533, Issue 7, July 2025.
A detailed structural analysis of the juvenile swine ventricular–subventricular zone reveals four distinct cellular layers and diverse neuroblast migration routes, including pathways toward the olfactory bulb and cortical regions. These features underscore the swine brain's value as a translational model for studying postnatal neurogenesis in large ...
Lucía Inés Torrijos‐Saiz   +6 more
wiley   +1 more source

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