Results 101 to 110 of about 9,892 (240)

Pharmacokinetics, pharmacodynamics and safety of 15 mg-tolvaptan administered orally for 7 consecutive days to Chinese patients with child-Pugh B cirrhosis

open access: yesFrontiers in Pharmacology
Background: Tolvaptan, a selective vasopressin V2-receptor antagonist, can elicit a diuretic effect without significant electrolyte loss. The aims were to evaluate multiple-dose pharmacokinetics, pharmacodynamics and safety of daily administration of 15 ...
Hongzhong Liu   +10 more
doaj   +1 more source

Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy [PDF]

open access: yes, 2017
The global nephrology community recognises the need for a cohesive plan to address the problem of chronic kidney disease (CKD). In July, 2016, the International Society of Nephrology hosted a CKD summit of more than 85 people with diverse expertise and ...
Bonventre, J   +26 more
core  

Duloxetine-Induced Antidiuresis in Rats with Lithium-Induced Nephrogenic Diabetes Insipidus

open access: yesLife
Antidepressants, including duloxetine, are a significant cause of drug-induced hyponatremia, which can disrupt the continuation of medication. Tolvaptan is beneficial for correcting hyponatremia caused by the syndrome of inappropriate antidiuresis, but ...
Sua Kim, Chor Ho Jo, Gheun-Ho Kim
doaj   +1 more source

Immediate drop of urine osmolality upon tolvaptan initiation predicts impact on renal prognosis in patients with ADPKD [PDF]

open access: bronze, 2023
Taro Akihisa   +12 more
openalex   +1 more source

Insights into autosomal dominant polycystic kidney disease by quantitative mass spectrometry-based proteomics [PDF]

open access: yes, 2018
Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenetic disorder that is caused by mutations in the genes PKD1 and PKD2 encoding polycystin-1 and polycystin-2, respectively.
Dengjel, Jörn, Diedrich, Britta
core  

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