Results 21 to 30 of about 179,231 (267)

Dcf1 Deficiency Attenuates the Role of Activated Microglia During Neuroinflammation

Frontiers in Molecular Neuroscience, 2018
Microglia serve as the principal immune cells and play crucial roles in the central nervous system, responding to neuroinflammation via migration and the execution of phagocytosis. Dendritic cell-derived factor 1 (Dcf1) is known to play an important role
Jiao Wang, Jie Li, Qian Wang, Yanyan Kong, Fangfang Zhou, Qian Li, Weihao Li, Yangyang Sun, Yanli Wang, Yihui Guan, Minghong Wu, Tieqiao Wen   +11 more
doaj   +1 more source

A Potential Prognostic Marker for Recognizing VEGF-Positive Hepatocellular Carcinoma Based on Magnetic Resonance Radiomics Signature

Frontiers in Oncology, 2022
ObjectivesThe objective of our project is to explore a noninvasive radiomics model based on magnetic resonance imaging (MRI) that could recognize the expression of vascular endothelial growth factor (VEGF) in hepatocellular carcinoma before operation ...
Tingting Fan, Shijie Li, Kai Li, Jingxu Xu, Sheng Zhao, Jinping Li, Xinglu Zhou, Huijie Jiang   +7 more
doaj   +1 more source

Superiority of 18F-FNa PET/CT for Detecting Bone Metastases in Comparison with Other Diagnostic Imaging Modalities

Acta Médica Portuguesa, 2017
Introduction: The 18F-NaF positron emission tomography/computed tomography is being considered as an excellent imaging modality for bone metastases detection. This ability was compared with other imaging techniques.
Paula Lapa, Tiago Saraiva, Rodolfo Silva, Margarida Marques, Gracinda Costa, João Pedroso Lima   +5 more
doaj   +1 more source

Intrathoracic Goiter Visualized on iodine-123 and technetium-99m Single-Photon Emission Computed Tomography/Computed Tomography

World Journal of Nuclear Medicine, 2021
Goiter with an intrathoracic component is relatively common; however, it is less common to see extent outside the anterior or posterior mediastinum. We present a case of intrathoracic goiter of significant size and abnormal placement which is examined ...
Mattias Kristensen, Jan Abrahamsen, Henrik Thomsen   +2 more
doaj   +1 more source

Correlation between PET/CT and CT in the staging prior to the treatment of head and neck squamous cell carcinoma

Brazilian Journal of Otorhinolaryngology, 2021
Introduction: Head and neck squamous cell carcinoma is the seventh most common malignant tumor. The advances in treatment have improved the global survival rates in the past years, although the prognosis is still grave.
Fernando García-Curdi, Yolanda Lois-Ortega, Ana Muniesa-del Campo, Amaranta McGee-Laso, José Miguel Sebastián-Cortés, Héctor Vallés-Varela, Julio José Lambea-Sorrosal   +6 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Central hyperthyroidism due to an ectopic TSH-secreting pituitary tumor: a case report and literature review

Frontiers in Endocrinology
Ectopic thyroid-stimulating hormone (TSH)-secreting tumors are extremely rare, with only 15 reported cases in the literature. Herein, we described a 60-year-old female patient with thyrotoxicosis and elevated or unsuppressed levels of TSH. Family history
Chonggui Zhu, Tong Liu, Haonan Yu, Lina Chang, Xiaona Zhang, Jia Yao, Geng Zhang, Qiusong Chen, Qing He, Ming Liu   +9 more
doaj   +1 more source

Positron emission tomography/computed tomography surveillance in patients with Hodgkin lymphoma in first remission has a low positive predictive value and high costs

Haematologica, 2012
Background The value of performing post-therapy routine surveillance imaging in patients with Hodgkin lymphoma is controversial. This study evaluates the utility of positron emission tomography/computed tomography using 2-[18F]fluoro-2-deoxyglucose for ...
Tarec Christoffer El-Galaly, Karen Juul Mylam, Peter Brown, Lena Specht, Ilse Christiansen, Lars Munksgaard, Hans Erik Johnsen, Annika Loft, Anne Bukh, Victor Iyer, Anne Lerberg Nielsen, Martin Hutchings   +11 more
doaj   +1 more source

Prognostic value of 18F-FDG PET/CT parameters and histopathologic variables in head and neck cancer

Brazilian Journal of Otorhinolaryngology, 2021
Introduction: 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters such as; maximum standardized uptake values, standard metabolic tumor volume and otal lesion glycosis are important prognostic biomarkers in cancers ...
Hale Aslan, Gul Cekin, Ercan Pinar, Mustafa Yazir, Abdulkadir Imre, Murat Songu, Akif Islek, Ibrahim Aladag, Ismail Semih Oncel   +8 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source