Results 61 to 70 of about 477,223 (297)
Realistic CT image simulation tools for laboratory based X-ray CT at UGCT [PDF]
, 2013 In laboratory based X-ray Computed Tomography (CT), the grey values in the resulting CT image depend on several scanning conditions such as the emitted spectrum, the response characteristics of the detector and beam filtration.
Brabant, Loes +3 more
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Two-view topogram-based anatomy-guided CT reconstruction for prospective risk minimization
Scientific ReportsTo facilitate a prospective estimation of the effective dose of an CT scan prior to the actual scanning in order to use sophisticated patient risk minimizing methods, a prospective spatial dose estimation and the known anatomical structures are required.
Chang Liu +6 more
doaj +1 more source
X-ray Digital Radiography and Computed Tomography
Journal of Imaging, 2022 In recent years, X-ray imaging has rapidly grown and spread beyond the medical field; today, it plays a key role in diverse research areas [...]
Maria Pia Morigi, Fauzia Albertin
doaj +1 more source
A Convex Reconstruction Model for X-ray Tomographic Imaging with Uncertain Flat-fields [PDF]
, 2017 Classical methods for X-ray computed tomography are based on the assumption that the X-ray source intensity is known, but in practice, the intensity is measured and hence uncertain.
Aggrawal, Hari Om +3 more
core +2 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
WEST tokamak hard x-ray tomography inversion
AIP Advances, 2021 Long-pulse steady-state discharges with lower hybrid current drive were successfully obtained in the limiter configuration machine, Tore Supra. The hard x-ray (HXR) diagnostic system in Tore Supra associated with tomographic inversion provided a good ...
K. Wongrach +5 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source