Results 61 to 70 of about 1,267,305 (324)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Neutrino tomography of the earth [PDF]
Proceedings of Neutrino Oscillation Workshop — PoS(NOW2018), 2018 Cosmic-ray interactions with the nuclei of the Earth's atmosphere produce a flux of neutrinos in all directions with energies extending above the TeV scale. However, the Earth is not a fully transparent medium for neutrinos with energies above a few TeV.
Andrea Donini +3 more
openaire +5 more sources
The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum
FEBS Letters, EarlyView.In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti +3 more
wiley +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
A mathematical approach towards THz tomography for non-destructive imaging [PDF]
arXiv, 2020 In this paper, we consider the imaging problem of terahertz (THz) tomography, in particular as it appears in non-destructive testing. We derive a nonlinear mathematical model describing a full THz tomography experiment, and consider linear approximations connecting THz tomography with standard computerized tomography and the Radon transform.
arxiv
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source
Imaging polar and dipolar sources of geophysical anomalies by probability tomography. Part I: theory and synthetic examples [PDF]
Progress In Electromagnetics Research, vol. 87, 63-88, 2008, 2006 We develop the theory of a generalized probability tomography method to image source poles and dipoles of a geophysical vector or scalar field dataset. The purpose of the new generalized method is to improve the resolution power of buried geophysical targets, using probability as a suitable paradigm allowing all possible equivalent solution to be ...
arxiv +1 more source
Journal of Physics G: Nuclear and Particle Physics, 2004 Plenary talk given at the seventeenth international conference on Ultra-Relativistic Nucleus-Nucleus Collisions (Quark Matter 2004). 8 pages, 12 figures.
openaire +2 more sources
FEBS Letters, EarlyView.Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez +3 more
wiley +1 more source
Erdheim-Chester Disease: Utility of 18F-FDG Positron Emission Tomography [PDF]
Journal of Clinical and Diagnostic Research, 2018 Erdheim-Chester Disease (ECD) is a rare non Langerhans cell histiocytosis of unknown origin with multiorgan involvement. We report a case of a man who presented to us with haematuria, asthenia, fever, nausea and malleolar oedema.
Angelina Cistaro +4 more
doaj +1 more source