Results 1 to 10 of about 1,879,593 (306)
Nature Communications, 2019 Processing bodies are membrane less organelles that contain enzymes involved in mRNA turnover, among them enhancer of decapping 3 (Edc3). Here the authors use solid- and solution-state NMR spectroscopy to characterize the structural organization and ...
Reinier Damman +5 more
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The Cell Surface, 2020 Cell walls are essential in the interaction of fungi with the (a)biotic environment and are also key to hyphal morphogenesis and mechanical strength. Here, we used solid-state NMR (ssNMR) spectroscopy combined with HPLC and GC–MS to study the structural ...
Helena Leona Ehren +5 more
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Shifts in the selectivity filter dynamics cause modal gating in K+ channels
Nature Communications, 2019 Spontaneous activity shifts at constant experimental conditions are widespread among ion channels but the molecular origins are poorly understood. Here, using solid-state NMR and MD simulations, the authors reveal that modal gating shifts in K + channels
Shehrazade Jekhmane +7 more
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Probing Nuclear Dipole Moments and Magnetic Shielding Constants through 3-Helium NMR Spectroscopy
Physchem, 2022 Multinuclear NMR studies of the gaseous mixtures that involve volatile compounds and 3He atoms are featured in this review. The precise analyses of 3He and other nuclei resonance frequencies show linear dependencies on gas density.
Włodzimierz Makulski
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Biological solid-state NMR: Integrative across different scientific disciplines
Journal of Structural Biology: X, 2022 For almost five decades, solid-state NMR (ssNMR) has been used to study complex biomolecular systems. This article gives a view on how ssNMR methods and applications have evolved during this time period in a broader structural biology context.
Marc Baldus
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Mode of action of teixobactins in cellular membranes
Nature Communications, 2020 The natural antibiotic teixobactin kills bacteria by direct binding to their cognate cell wall precursors (Lipid II and III). Here authors use solid-state NMR to reveal the native binding mode of teixobactins and show that teixobactins only weakly bind ...
Rhythm Shukla +14 more
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Binding of micro-nutrients to the cell wall of the fungus Schizophyllum commune
The Cell Surface, 2023 The cell wall fulfils several functions in the biology of fungi. For instance, it provides mechanical strength, interacts with the (a)biotic environment, and acts as a molecular sieve.
Fleur E.L. Kleijburg +3 more
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Pharmaceutics, 2021 At present, the risk of generic substitutions in warfarin tablets is still being discussed. The aim of this study was to assess whether API interactions with commonly used excipients may affect the safety of generic replacement of warfarin sodium tablets.
Jan Muselík +9 more
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NeurogliaElectroconvulsive therapy (ECT) is an effective treatment for severe and drug-resistant depression, yet its mode of action remains poorly understood.
Ajay Sarawagi +5 more
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A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system
Molecular Systems Biology, 2009 Covalent attachment of ubiquitin to substrates is crucial to protein degradation, transcription regulation and cell signalling. Highly specific interactions between ubiquitin‐conjugating enzymes (E2) and ubiquitin protein E3 ligases fulfil essential ...
Sjoerd J L van Wijk +6 more
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