Results 31 to 40 of about 1,879,593 (306)

Combining NMR spectroscopy and organic synthesis : from small building blocks to large biomolecules [PDF]

, 2014
Detailed knowledge of the structure of bio molecules with atomic resolution is essential for the understanding of their function. Moreover the identification and quantification of their dynamic processes are important, as they are the origin of molecular
Gsellinger, Heiko
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Protein NMR spectroscopy [PDF]

Current Biology, 1998
Protein NMR spectroscopy does have its limitations. It has so far been used mainly for small proteins with molecular weight of less than 30 kDa, although a handful of publications have now reported the NMR study of proteins up to 40–50 kDa. Larger proteins typically have faster relaxation rates, which results in fatter NMR peaks that tend to merge with
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An inter-laboratory comparison demonstrates that [H-1]-NMR metabolite fingerprinting is a robust technique for collaborative plant metabolomic data collection. [PDF]

, 2010
In any metabolomics experiment, robustness and reproducibility of data collection is of vital importance. These become more important in collaborative studies where data is to be collected on multiple instruments.
Biais, Benoit, Beale, Michael H., Sofia Moco, Jacques Vervoort, Maucourt, Mickael,, Ward, J.L., Michael H. Beale, Lommen, Arjen, Rolin, D., Maucourt, Mickael, M., Moco, Sofia, Vervoort, J., Baker, J. M., Humpfer, Eberhard, Deborde, C., Beale, M.H., Ward, J. L., Deborde, Catherine,, Maucourt, M., Mickael Maucourt, Beale, M. H., Annick Moing, Lommen, A., Jane L. Ward, Vervoort, J.J.M., Hartmut Schäfer, Schäfer, Hartmut, Deborde, Catherine, Baker, J.M., Arjen Lommen, Miller, S.J., Vervoort, Jacques, Eberhard Humpfer, Miller, Sonia J., Rolin, Dominique, D., Moco, S.I.A., Rolin, Dominique,, John M. Baker, Baker, John M., Benoit Biais, Catherine Deborde, Moco, S., Ward, Jane L., Biais, B., Dominique Rolin, Moing, Annick, Humpfer, E., Moing, A., Miller, S. J., Sonia J. Miller, Schafer, H., Maucourt, Mickael, Beale, Mike, Rolin, Dominique, Ward, Jane   +54 more
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Ultrahigh‐Resolution NMR Spectroscopy [PDF]

Angewandte Chemie International Edition, 2014
All psyched up: A flexible and general pure shift experiment (PSYCHE) has been developed that offers superior sensitivity, spectral purity, and tolerance of strong coupling over existing methods for broadband homonuclear decoupling. The partial spectra of estradiol in [D6]DMSO obtained by normal 1H NMR spectroscopy and PSYCHE are shown for comparison.
Foroozandeh, Mohammadali, Adams, Ralph W; id_orcid 0000-0001-8009-5334, Meharry, Nicola J, Jeannerat, Damien, Nilsson, Mathias; id_orcid 0000-0003-3301-7899, Morris, Gareth A; id_orcid 0000-0002-4859-6259   +5 more
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High-resolution NMR structure of an RNA model system : the 14-mer cUUCGg tetraloop hairpin RNA [PDF]

, 2010
We present a high-resolution nuclear magnetic resonance (NMR) solution structure of a 14-mer RNA hairpin capped by cUUCGg tetraloop. This short and very stable RNA presents an important model system for the study of RNA structure and dynamics using NMR ...
Nozinovic, Senada, Fürtig, Boris, Jonker, Hendrik R. A., Schwalbe, Harald (Prof. Dr.), Richter, Christian   +4 more
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Studies of carbohydrate structure, properties and interactions by nmr spectroscopy [PDF]

, 2013
In this thesis the structure, properties and interactions of different types of carbohydrates were investigated by NMR spectroscopy. The structures of kappa- (κ) and kappa/mu- (κ/μ) carrageenan oligosaccharides were analyzed by studying the hydroxy ...
Morssing Vilén, Eric
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NMR Spectroscopy for Metabolomics Research [PDF]

Metabolites, 2019
Over the past two decades, nuclear magnetic resonance (NMR) has emerged as one of the three principal analytical techniques used in metabolomics (the other two being gas chromatography coupled to mass spectrometry (GC-MS) and liquid chromatography coupled with single-stage mass spectrometry (LC-MS)). The relative ease of sample preparation, the ability
Abdul-Hamid Emwas, Raja Roy, Ryan T. McKay, Leonardo Tenori, Edoardo Saccenti, G. A. Nagana Gowda, Daniel Raftery, Fatimah Alahmari, Lukasz Jaremko, Mariusz Jaremko, David S. Wishart   +10 more
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Saturation Transfer Difference NMR Spectroscopy Using Glycopolymers [PDF]

, 2020
We report the use of Saturation Transfer Difference (STD) NMR spectroscopy to observe the interaction of various phenylboronic acids (PBAs) with synthetic glycopolymers presenting galactose and glucose.
janet, muzulu, Amit, Basu
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High-resolution NMR studies of antibiotics in cellular membranes

Nature Communications, 2018
Antibiotics that target the peptidoglycan precursor lipid II are promising templates for next-generation antibiotics. Here authors use solid-state NMR and monitor lipid II-binding antibiotics, such as nisin, directly in cell membranes.
João Medeiros-Silva, Shehrazade Jekhmane, Alessandra Lucini Paioni, Katarzyna Gawarecka, Marc Baldus, Ewa Swiezewska, Eefjan Breukink, Markus Weingarth   +7 more
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Binding hotspots of BAZ2B bromodomain:histone interaction revealed by solution NMR driven docking [PDF]

, 2014
Bromodomains are epigenetic reader domains, which have come under increasing scrutiny both from academic and pharmaceutical research groups. Effective targeting of the BAZ2B bromodomain by small molecule inhibitors has been recently reported, but no ...
Ferguson, Fleur M., Alexandre M. J. J. Bonvin (18079), Alexandre M. J. J. Bonvin, João P. G. L. M. Rodrigues (1312506), Wienk, Hans, Fleur M. Ferguson (1304613), Rolf Boelens (18078), Alessio Ciulli, Boelens, Rolf, NMR Spectroscopy, Chris Abell, Fleur M. Ferguson, Garcia Lopes Maia Rodrigues, João, Rodrigues, João P. G. L. M., David M. Dias, Bonvin, Alexandre M. J. J., Sub NMR Spectroscopy, Dias, David M., João P. G. L. M. Rodrigues, David M. Dias (1340694), Rolf Boelens, Abell, Chris, Hans Wienk (684663), Ciulli, Alessio, Hans Wienk, Chris Abell (197099), Alessio Ciulli (762789)   +26 more
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