Results 31 to 40 of about 566,413 (348)
Binding of micro-nutrients to the cell wall of the fungus Schizophyllum commune
The cell wall fulfils several functions in the biology of fungi. For instance, it provides mechanical strength, interacts with the (a)biotic environment, and acts as a molecular sieve.
Fleur E.L. Kleijburg +3 more
doaj +1 more source
At present, the risk of generic substitutions in warfarin tablets is still being discussed. The aim of this study was to assess whether API interactions with commonly used excipients may affect the safety of generic replacement of warfarin sodium tablets.
Jan Muselík +9 more
doaj +1 more source
Accurate DOSY measure of out-of-equilibrium systems by permutated DOSY (p-DOSY) [PDF]
NMR spectroscopy is an excellent tool for monitoring in-situ chemical reactions. In particular, DOSY measurement is well suited to characterize transient species by the determination of their sizes.
Delsuc, Marc-André +3 more
core +5 more sources
Opening the black box of mixed-metal TMP metallating reagents : direct cadmation or lithium-cadmium transmetallation? [PDF]
Designed to remove some of the mystery surrounding mixed-metal TMP (2,2,6,6-tetramethylpiperidide) metallating reagents, this study examines in detail "LiCd(TMP)(3)'' in its own right.
Alborés +41 more
core +1 more source
Electroconvulsive therapy (ECT) is an effective treatment for severe and drug-resistant depression, yet its mode of action remains poorly understood.
Ajay Sarawagi +5 more
doaj +1 more source
A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system
Covalent attachment of ubiquitin to substrates is crucial to protein degradation, transcription regulation and cell signalling. Highly specific interactions between ubiquitin‐conjugating enzymes (E2) and ubiquitin protein E3 ligases fulfil essential ...
Sjoerd J L van Wijk +6 more
doaj +1 more source
High-resolution NMR studies of antibiotics in cellular membranes
Antibiotics that target the peptidoglycan precursor lipid II are promising templates for next-generation antibiotics. Here authors use solid-state NMR and monitor lipid II-binding antibiotics, such as nisin, directly in cell membranes.
João Medeiros-Silva +7 more
doaj +1 more source
A phytochemical comparison of saw palmetto products using gas chromatography and (1) H nuclear magnetic resonance spectroscopy metabolomic profiling [PDF]
© 2014 The Authors. Journal of Pharmacy and Pharmacology published by John Wiley & Sons Ltd on behalf of Royal Pharmaceutical Society. This is an open access article under the terms of the Creative Commons Attribution License, which permits use ...
Booker, Anthony +6 more
core +1 more source
Early Stage Diagnosis of Oral Cancer Using 1H NMR–Based Metabolomics
Oral cancer is the eighth most common cancer worldwide and represents a significant disease burden. If detected at an early stage, survival from oral cancer is better than 90% at 5 years, whereas late stage disease survival is only 30%.
Stefano Tiziani +2 more
doaj +1 more source
Microtubule (MT) organization is regulated by many microtubule-associated proteins (MAPs) that contain intrinsically disordered regions. Here authors produce [13C, 15N] labeled, functional microtubules from human cells for solid-state NMR which allows ...
Yanzhang Luo +8 more
doaj +1 more source

