Results 21 to 30 of about 1,879,593 (306)
Structural characterization of intrinsically disordered proteins by NMR spectroscopy. [PDF]
, 2013 Recent advances in NMR methodology and techniques allow the structural investigation of biomolecules of increasing size with atomic resolution. NMR spectroscopy is especially well-suited for the study of intrinsically disordered proteins (IDPs) and ...
Contreras-Martos, Sara +7 more
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Molecules, 2022 In crystalline molecular solids, in the absence of strong intermolecular interactions, entropy-driven processes play a key role in the formation of dynamically modulated transient phases.
Jiri Brus +3 more
doaj +1 more source
In-cell NMR spectroscopy [PDF]
Progress in Nuclear Magnetic Resonance Spectroscopy, 2011 Interactions between biological macromolecules give rise to and regulate biological activity. This activity is manifest through structural dynamics and changes in the macromolecular structures that comprise these interactions [1-3]. Until recently, mostly in vitro techniques have been used to study macromolecular interactions that govern biological ...
Andres Y, Maldonado +2 more
openaire +2 more sources
Protein folding on the ribosome studied using NMR spectroscopy [PDF]
, 2013 NMR spectroscopy is a powerful tool for the investigation of protein folding and misfolding, providing a characterization of molecular structure, dynamics and exchange processes, across a very wide range of timescales and with near atomic resolution.
Christodoulou, J +7 more
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Frontiers in Molecular Neuroscience, 2017 Alzheimer’s disease (AD) is an age-related neurodegenerative disorder, characterized by progressive loss of cognitive functions and memory. Excessive intake of aluminum chloride in drinking water is associated with amyloid plaques and neurofibrillary ...
Kamal Saba +6 more
doaj +1 more source
Formation of the β-barrel assembly machinery complex in lipid bilayers as seen by solid-state NMR
Nature Communications, 2018 The β-barrel assembly machinery (BAM) catalyzes β-barrel protein insertion into the outer membrane of E.coli. Here authors employ high-sensitivity solid-state NMR to reveal how the lipid environment and formation of the BamA-BamCDE complex affect BamA ...
Cecilia Pinto +5 more
doaj +1 more source
Membranes, 2015 Phosphatidylinositol 3-kinase-related kinases (PIKKs) play vital roles in the regulation of cell growth, proliferation, survival, and consequently metabolism, as well as in the cellular response to stresses such as ionizing radiation or redox changes. In
Maristella De Cicco +2 more
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A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V
Nature Communications, 2022 Constriction of the selectivity filter is assumed to be a hallmark of C-type inactivation in K+ channels. Using different high-resolution methods, this study shows a distinct C-type inactivation mechanism in a KcsA mutant that emulates Kv-channels.
Ahmed Rohaim +8 more
doaj +1 more source
High-resolution solid state NMR experiments for the characterization of calcium phosphate biomaterials and biominerals [PDF]
, 2011 Calcium phosphates form a vast family of biominerals, which have attracted much attention in fields like biology, medicine, and materials science, to name a few.
Hanna, John +55 more
core +5 more sources
Exploiting periodic first-principles calculations in NMR spectroscopy of disordered solids [PDF]
, 2013 Much of the information contained within solid-state nuclear magnetic resonance (NMR) spectra remains unexploited because of the challenges in obtaining high-resolution spectra and the difficulty in assigning those spectra.
Ashbrook, Sharon Elizabeth +3 more
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