Results 11 to 20 of about 309,964 (310)

Solid‐State NMR Spectroscopy on Complex Biomolecules

open access: yesAngewandte Chemie - International Edition, 2010
Biomolecular applications of NMR spectroscopy are often merely associated with soluble molecules or magnetic resonance imaging. However, since the late 1970s, solid-state NMR (ssNMR) spectroscopy has demonstrated its ability to provide atomic-level ...
Marie Renault, Marc Baldus
exaly   +2 more sources

NMR Spectroscopy in Bioinorganic Chemistry

open access: yesCHIMIA, 2012
Multinuclear and multidimensional nuclear magnetic resonance (NMR) spectroscopy is applied in our groups to gain insights into the role of metal ions for the function and structure of large biomolecules.
Daniela Donghi   +3 more
doaj   +6 more sources

Hyperdimensional NMR Spectroscopy [PDF]

open access: yesJournal of the American Chemical Society, 2006
Hyperdimensional NMR describes the multiple interactions between a large number, N, of coupled nuclear spins. We show how to construct a hypothetical N-dimensional spectrum from a limited set of low-dimensional measurements, exploiting the concept of projection-reconstruction.
Eriks, Kupce, Ray, Freeman
openaire   +2 more sources

In-Cell NMR Spectroscopy [PDF]

open access: yesChemBioChem, 2005
The role of a protein inside a cell is determined by both its location and its conformational state. Although fluorescence techniques are widely used to determine the cellular localization of proteins in vivo, these approaches cannot provide detailed information about a protein's three-dimensional state.
Zach, Serber   +3 more
openaire   +4 more sources

Nuclear Dipole Moments and Shielding Constants of Light Nuclei Measured in Magnetic Fields

open access: yesMagnetochemistry, 2023
Nuclear magnetic resonance (NMR) is a branch of spectroscopy commonly used for identifying the chemical structure of various materials. One of the areas in which NMR provides accurate data is the determination of nuclear magnetic moments.
Włodzimierz Makulski   +2 more
doaj   +1 more source

Glutamate and GABA Homeostasis and Neurometabolism in Major Depressive Disorder

open access: yesFrontiers in Psychiatry, 2021
Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As per the latest WHO report, MDD affects more than 260 million people worldwide.
Ajay Sarawagi   +4 more
doaj   +1 more source

Characterization of a fold in TANGO1 evolved from SH3 domains for the export of bulky cargos

open access: yesNature Communications, 2023
Bulky cargos like procollagens, apolipoproteins, and mucins exceed the size of conventional COPII vesicles. During evolution a process emerged in metazoans, predominantly governed by the TANGO1 protein family, that organizes cargo at the exit sites of ...
Oliver Arnolds, Raphael Stoll
doaj   +1 more source

Searching for the Best Values of NMR Shielding and Spin-Spin Coupling Parameters: CH4-nFn Series of Molecules as the Example

open access: yesMolecules, 2023
Attempts at the theoretical interpretation of NMR spectra have a very long and fascinating history. Present quantum chemical calculations of shielding and indirect spin-spin couplings permit modeling NMR spectra when small, isolated molecules are studied.
Karol Jackowski, Mateusz A. Słowiński
doaj   +1 more source

In-cell NMR spectroscopy [PDF]

open access: yesProgress in Nuclear Magnetic Resonance Spectroscopy, 2011
Interactions between biological macromolecules give rise to and regulate biological activity. This activity is manifest through structural dynamics and changes in the macromolecular structures that comprise these interactions [1-3]. Until recently, mostly in vitro techniques have been used to study macromolecular interactions that govern biological ...
Andres Y, Maldonado   +2 more
openaire   +2 more sources

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