Results 181 to 190 of about 34,712 (249)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

Cardioneuroablation Restoring Atrioventricular Conduction in Brugada Syndrome: A Device-Free Approach. [PDF]

open access: yesJACC Case Rep
Chipa-Ccasani F   +9 more
europepmc   +1 more source

Glioblastoma radiomics can delineate systemic immune activity states like blood abundance of T cell populations or transcription factors. [PDF]

open access: yesJ Neuroinflammation
Heugenhauser J   +9 more
europepmc   +1 more source

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