Results 51 to 60 of about 1,358,598 (243)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
The closed-form robust Chinese Remainder Theorem (CRT) is a powerful approach to achieve single-frequency estimation from noisy undersampled waveforms. However, the difficulty of CRT-based methods’ extension into the multi-tone case lies in the fact it ...
Xiangdong Huang, Lu Cao, Wei Lu
doaj +1 more source
Feature-preserving color pencil drawings from photographs
Color pencil drawing is well-loved due to its rich expressiveness. This paper proposes an approach for generating feature-preserving color pencil drawings from photographs.
Dong Wang +4 more
doaj +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
HDR Image Quality Enhancement Based on Spatially Variant Retinal Response
There is a growing demand for being able to display high dynamic range (HDR) images on low dynamic range (LDR) devices. Tone mapping is a process for enhancing HDR image quality on an LDR device by converting the tonal values of the original image from ...
Horiuchi Takahiko, Tominaga Shoji
doaj
A Weighted Histogram-Based Tone Mapping Algorithm for CT Images
Computed Tomography (CT) images have a high dynamic range, which makes visualization challenging. Histogram equalization methods either use spatially invariant weights or limited kernel size due to the complexity of pairwise contribution calculation.
David Völgyes +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Sonification as a possible stroke rehabilitation strategy
Despite cerebral stroke being one of the main causes of acquired impairments of motor skills worldwide, well-established therapies to improve motor functions are sparse.
Daniel S. Scholz +6 more
doaj +1 more source

