Results 1 to 10 of about 49,453 (252)

Towards a UK federation of trusted research environments

open access: yesInternational Journal of Population Data Science
Objectives Phase 1 of the DARE UK programme concluded in 2024 with a portfolio of architectures, designs and proofs-of-concept for a national federated network of trusted research environments (TREs).
Rob Baxter, DARE UK Delivery Team
doaj   +1 more source

Pathological complete response with immunotherapy and brachytherapy to 15 metastatic liver lesions in a single patient

open access: yesHepatic Oncology, 2022
Materials & methods: High dose rate interstitial brachytherapy (HDR-IBT) treatment plan for 15 metastatic liver lesions in a patient with pancreatic cancer was retrieved and analyzed for liver dose parameters and diaphragm dose.
Gokula Kumar Appalanaido   +6 more
doaj   +1 more source

Stable Cells with NF-κB-ZsGreen Fused Genes Created by TALEN Editing and Homology Directed Repair for Screening Anti-inflammation Drugs

open access: yesJournal of Inflammation Research, 2021
Shuyan Zhang, Tao Luo, Jinke Wang State Key Laboratory of Bioelectronics, Southeast University, Nanjing, 210096, People’s Republic of ChinaCorrespondence: Jinke WangState Key Laboratory of Bioelectronics, Southeast University, Nanjing, 210096 ...
Zhang S, Luo T, Wang J
doaj  

Learning-Based JND-Directed HDR Video Preprocessing for Perceptually Lossless Compression With HEVC

open access: yesIEEE Access, 2020
The final consumer of videos is mostly human. Therefore, if videos can be compressed by fully utilizing the perception characteristics of human visual systems (HVS), the bitrates of the compressed videos can be significantly reduced with subjective ...
Sehwan Ki, Jeonghyeok Do, Munchurl Kim
doaj   +1 more source

Co-producing Public involvement and Engagement Guidance in Health Data Research Involving Unique Property Reference Numbers

open access: yesInternational Journal of Population Data Science
Objectives Unique Property Reference Numbers (UPRNs) encode publicly available address data, which can be linked to confidential and sensitive health or personal data. We brought together researchers and members of the public to create specific guidance
Julia Shumway   +4 more
doaj   +1 more source

Towards standardised cross-sectoral agreements for data depositing and data access in Trusted Research Environments: streamlined contracting to advance public benefit research. 

open access: yesInternational Journal of Population Data Science
Objective  Trusted Research Environments (TREs) rely on Data Contributor Agreements (DCAs) and Data Access Agreements (DAAs) to bind organisations to terms and conditions in place to protect data.
Rachel Brophy   +3 more
doaj   +1 more source

Progress and prospect of hot dry rock exploration and development

open access: yesShuiwen dizhi gongcheng dizhi, 2023
The exploitation and utilization of clean energy is a resource and environmental issue of common concern for global sustainable development. As a vital strategic and sustainable future energy, hot dry rock (HDR) has attracted more and more attention.
Dongguang WEN   +14 more
doaj   +1 more source

Stereo Vision-Based High Dynamic Range Imaging Using Differently-Exposed Image Pair

open access: yesSensors, 2017
In this paper, a high dynamic range (HDR) imaging method based on the stereo vision system is presented. The proposed method uses differently exposed low dynamic range (LDR) images captured from a stereo camera.
Won-Jae Park   +4 more
doaj   +1 more source

Enhancement of CRISPR-Cas9 induced precise gene editing by targeting histone H2A-K15 ubiquitination

open access: yesBMC Biotechnology, 2020
Background Precise genetic modifications are preferred products of CRISPR-Cas9 mediated gene editing in mammalian cells but require the repair of induced double-strand breaks (DSB) through homology directed repair (HDR).
Sanum Bashir   +4 more
doaj   +1 more source

Optimized design parameters for CRISPR Cas9 and Cas12a homology-directed repair

open access: yesScientific Reports, 2021
CRISPR–Cas proteins are RNA-guided nucleases used to introduce double-stranded breaks (DSBs) at targeted genomic loci. DSBs are repaired by endogenous cellular pathways such as non-homologous end joining (NHEJ) and homology-directed repair (HDR ...
Mollie S. Schubert   +7 more
doaj   +1 more source

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