Results 81 to 90 of about 34,712 (249)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
IET Computer Vision, 2016 Many tone‐mapping methods have developed efficient tone compression and local contrast enhancement techniques for high dynamic‐range imaging. Local tone mapping enhances the image quality to reveal the details; however, it causes artefacts such as halos.
Hyuk‐Ju Kwon +3 more
doaj +1 more source
A Re-examination of Dichoptic Tone Mapping. [PDF]
ACM Trans Graph, 2021 Wang M, Cooper EA.
europepmc +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Enhancing a Display’s Sunlight Readability with Tone Mapping
PhotonicsThe sunlight readability of display devices, such as notebook computers, transparent displays, vehicle displays, and augmented reality, is a significant technical challenge due to degraded image quality. To mitigate this problem, by fitting the human eye
Yizhou Qian +5 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
G-SemTMO: Tone Mapping With a Trainable Semantic Graph
IEEE AccessA Tone Mapping Operator (TMO) is required to render images with a High Dynamic Range (HDR) on media with limited dynamic capabilities. TMOs compress the dynamic range with the aim of preserving the visually perceptual cues of the scene.
Abhishek Goswami +5 more
doaj +1 more source