Results 81 to 90 of about 34,661 (250)
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Retinex Jointed Multiscale CLAHE Model for HDR Image Tone Compression
MathematicsTone-mapping algorithms aim to compress a wide dynamic range image into a narrower dynamic range image suitable for display on imaging devices. A representative tone-mapping algorithm, Retinex theory, reflects color constancy based on the human visual ...
Yu-Joong Kim, Dong-Min Son, Sung-Hak Lee
doaj +1 more source
High Dynamic Range Mapping for Synthetic Aperture Radar Images
Telfor Journal, 2018 Luminance compression is often performed for high dynamic range images (still images and videos). A nonlinear tone mapping is applied for the compression in order to reproduce high dynamic range images using devices with a more limited (low) dynamic ...
A. Gavrovska +5 more
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
IET Computer Vision, 2016 Many tone‐mapping methods have developed efficient tone compression and local contrast enhancement techniques for high dynamic‐range imaging. Local tone mapping enhances the image quality to reveal the details; however, it causes artefacts such as halos.
Hyuk‐Ju Kwon +3 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Enhancing a Display’s Sunlight Readability with Tone Mapping
PhotonicsThe sunlight readability of display devices, such as notebook computers, transparent displays, vehicle displays, and augmented reality, is a significant technical challenge due to degraded image quality. To mitigate this problem, by fitting the human eye
Yizhou Qian +5 more
doaj +1 more source