Results 81 to 90 of about 1,358,598 (243)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Retinex Jointed Multiscale CLAHE Model for HDR Image Tone Compression

open access: yesMathematics
Tone-mapping algorithms aim to compress a wide dynamic range image into a narrower dynamic range image suitable for display on imaging devices. A representative tone-mapping algorithm, Retinex theory, reflects color constancy based on the human visual ...
Yu-Joong Kim, Dong-Min Son, Sung-Hak Lee
doaj   +1 more source

High Dynamic Range Mapping for Synthetic Aperture Radar Images

open access: yesTelfor Journal, 2018
Luminance compression is often performed for high dynamic range images (still images and videos). A nonlinear tone mapping is applied for the compression in order to reproduce high dynamic range images using devices with a more limited (low) dynamic ...
A. Gavrovska   +5 more
doaj   +1 more source

[New Guinea, scale 1:63,360] [cartographic material] /

open access: yes, 1955
Provisional ed. Uncontoured (planimetric) map series of Papua New Guinea, compiled from aerial photography, showing minor roads, tracks, water features, buildings and populated places. Relief shown by spot heights.; Produced by National Mapping Office to
Australia. National Mapping Office.
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Singapore 1:25,000 road map [cartographic material] /

open access: yes, 1980
Ed. 3 SMU. Shows selected buildings, points of interest, and schools.; Base information, aerial photography dated Jan. 1974, Aug. 1979 and partial ground verification up to Jan. 1980.; "R.S.O. metric grid."; Some sheets include insets.; Includes lists of
Singapore. Ministry of Defence. Mapping Unit.
core  

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Enhanced high dynamic‐range image rendering using a surround map based on edge‐adaptive layer blurring

open access: yesIET Computer Vision, 2016
Many tone‐mapping methods have developed efficient tone compression and local contrast enhancement techniques for high dynamic‐range imaging. Local tone mapping enhances the image quality to reveal the details; however, it causes artefacts such as halos.
Hyuk‐Ju Kwon   +3 more
doaj   +1 more source

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