The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
This study examined the differential effects of surgical mask on Cantonese consonant, vowel, and tone perception. Forty native Cantonese adults were tested with the Cantonese consonant, vowel, and tone identification tasks.
William Choi +6 more
doaj +1 more source
Multiple Approaches of Neuro-Physiotherapy Used for Improving Balance, Normalizing Tone, and Gait Training in a Child With Ataxic Cerebral Palsy: A Case Report [PDF]
Dhanashree Upganlawar +3 more
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Age and growth of rose bitterling in Shin Tone River.
Gultneh Solomon +3 more
openalex +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Current and New Strategies for Managing Non-Responders to Laser Toning in the Treatment of Melasma
Young Woon Park, Un Cheol Yeo
openalex +2 more sources
Favourable outcome in idiopathic ventricular fibrillation with treatment aimed at prevention of high sympathetic tone and suppression of inducible arrhythmias. [PDF]
Harry J.G.M. Crijns +3 more
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Acoustics-turbulence interaction [PDF]
An investigation of the instability frequency was undertaken. Measurements revealed that the hot wire probe induces and sustains stable upstream oscillation of the free shear layer.
Hussain, A. K. M. F., Zaman, K. B. M. O.
core +1 more source

