Results 151 to 160 of about 1,605,291 (333)
Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Reflex Alterations in Venomotor Tone Produced by Venous Congestion [PDF]
Robert Alexander
openalex +1 more source
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani+14 more
wiley +1 more source
The effect of intensity and order on the apparent pitch of tones in the middle range. [PDF]
Rolland M. Stewart
openalex +1 more source
AbstractThis paper is a descriptive and analytic study of the tones and tone sandhi of the Southern Wu dialect of Lóngyóu (龙游), a city of c. 400,000 inhabitants located about 375 km southwest of Shanghai in Western Zhejiang Province, China. It is based on data collected in 2018 from two female native speakers.
Chen, Sherry Yong+1 more
openaire +1 more source
Macroscopic study of time unsteady noise of an aircraft engine during static tests [PDF]
Static tests of aircraft engines can exhibit greater than 10 db random unsteadiness of tone noise levels because flow disturbances that prevail near test site facilities are ingested.
Clark, B. J.+2 more
core +1 more source
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez+17 more
wiley +1 more source
Regional Vasomotor Tone in Normotensive and Hypertensive Dogs [PDF]
Arnold H. Williams, Henry A. Schroeder
openalex +1 more source
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source