Results 41 to 50 of about 395,145 (308)
AbstractThis paper is a descriptive and analytic study of the tones and tone sandhi of the Southern Wu dialect of Lóngyóu (龙游), a city of c. 400,000 inhabitants located about 375 km southwest of Shanghai in Western Zhejiang Province, China. It is based on data collected in 2018 from two female native speakers.
Chen, Sherry Yong +1 more
openaire +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Akustinių požymių koreliacijos svarba lietuvių kalbos priegaidžių skyrimui
Šiame tyrime iš naujo gvildenamas lietuvių kalbos tarmių priegaidžių (šįkart ilgųjų balsių) skyrimo klausimas. Pasitelkus eksperimentinę medžiagą iš šiaurinių žemaičių telšiškių tarmės, bandyta užčiuopti koreliacinius akustinių požymių (balsių trukmės ir
Evaldas Švageris
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Akoose has a comparatively complex verb morphology for a Bantu language. Underlying forms for the different morphemes making up the verb are proposed, as well as a set of segmental and tonal rules necessary to account for the surface forms.
Robert Hedinger
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
A spin to preserve contrast: Taiwanese tone sandhi
Chain-shifts, particularly circular ones such as the tone sandhi of Taiwanese Min has been a longstanding challenge to which phonologists of various persuasions have attempted. This paper appeals to markedness against contour tones in non-final positions
Wee, Lian-Hee
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