Results 61 to 70 of about 1,605,291 (333)

Aging-associated changes in microRNA expression profile of internal anal sphincter smooth muscle: Role of microRNA-133a. [PDF]

open access: yes, 2016
A comprehensive genomic and proteomic, computational, and physiological approach was employed to examine the (previously unexplored) role of microRNAs (miRNAs) as regulators of internal anal sphincter (IAS) smooth muscle contractile phenotype and basal ...
Addya, Sankar   +6 more
core   +3 more sources

The intracellular domain of TLR2 is capable of high‐affinity Zn binding: possible outcomes for the receptor activation

open access: yesFEBS Letters, EarlyView.
Toll‐like receptors (TLRs) are important in the innate immune system. This study explores the zinc‐binding ability of the TLR2 TIR domain (TLR2TIR). We found that TLR2TIR binds zinc with nanomolar affinity through its cysteine residues. Two of them, C673 and C713, are vital for receptor activation, indicating that zinc may play a role in initiating ...
Vladislav A. Lushpa   +8 more
wiley   +1 more source

A Review on Pharmacological Effects of Curcuma longa L. (Turmeric)

open access: yesJournal of Medicinal Plants, 2010
Background: Turmeric has a long history for food additive and medicinal uses. In Asian traditional medical systems turmeric has been expected to be a therapeutic or preventive agent for several human diseases including: gastrointestinal symptoms, liver ...
H Fallah Huseini   +2 more
doaj  

Main features of the Livonian sound system and pronunciation

open access: yesEesti ja Soome-ugri Keeleteaduse Ajakiri, 2016
The aim of this article is to give an overview of the Livonian sound system and pronunciation. Regarding Livonian dialectal variation, the main difference is between East and West Livonian, while Central Livonian forms a transition area. The basis of the
Tuuli Tuisk
doaj   +1 more source

The Effects of Finish Type on Permeability and Organoleptic Properties of Python (Python Reticulatus) Skin Finished Leather [PDF]

open access: yes, 2017
In the leather industry, there are many different types of finish, i.e. two-tone, transparent, semi aniline and opaque/solid color. The composition formulation of each finish type is different so each will impact not only on the performance but also on ...
Kasmudjiastuti, E. (Emiliana)   +1 more
core   +3 more sources

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Breast tuberculosis: A case report

open access: yesمجله دانشکده پزشکی اصفهان, 2008
Background: Tuberculosis infects one third of the world population and the leading of death worldwide. Lymphadenitis is the most frequent form of extra pulmonary tuberculosis.
Ahmad Alikhani   +2 more
doaj  

The Relation of Body Mass Index to Muscular Viscoelastic Properties in Normal and Overweight Individuals

open access: yesMedicina, 2021
Background: The body mass index (BMI) is closely related to fat tissue, which may have direct or indirect effects on muscle function. Previous studies have evaluated BMI and muscle viscoelastic properties in vivo in older people or individual sexes ...
Serkan Usgu   +2 more
doaj   +1 more source

Tone of Violins [PDF]

open access: yesNature, 1880
I SAW a little time back, but omitted to note it at the time, a brief notice of some German experiments showing that the strings of good old instruments of fine tone tended far more than in the case of inferior violins to vibrate in closed curves or simple curves.
openaire   +2 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

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