Results 131 to 140 of about 1,739,418 (322)

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

A Display-Adaptive Pipeline for Dynamic Range Expansion of Standard Dynamic Range Video Content

Applied Sciences
Recent advancements in high dynamic range (HDR) display technology have significantly enhanced the contrast ratios and peak brightness of modern displays. In the coming years, it is expected that HDR televisions capable of delivering significantly higher
Gonzalo Luzardo, Asli Kumcu, Jan Aelterman, Hiep Luong, Daniel Ochoa, Wilfried Philips   +5 more
doaj   +1 more source

Application of EREP imagery to fracture-related mine safety hazards and environmental problems in mining [PDF]

The author has identified the following significant results. All Skylab 2 imagery received to date has been analyzed manually and data related to fracture analysis and mined land inventories has been summarized on map-overlays.
Amato, R. V., Russell, O. R., Wier, C. E., Wobber, F. J.   +3 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Reconstructing High Dynamic Range Image from a Single Low Dynamic Range Image Using Histogram Learning

Applied Sciences
High dynamic range imaging is an important field in computer vision. Compared with general low dynamic range (LDR) images, high dynamic range (HDR) images represent a larger luminance range, making the images closer to the real scene.
Huei-Yung Lin, Yi-Rung Lin, Wen-Chieh Lin, Chin-Chen Chang   +3 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Single-Exposure HDR Image Translation via Synthetic Wide-Band Characteristics Reflected Image Training

Mathematics
High dynamic range (HDR) tone mapping techniques have been widely studied to effectively represent the broad dynamic range of real-world scenes. However, generating an HDR image from multiple low dynamic range (LDR) images captured at different exposure ...
Seung Hwan Lee, Sung Hak Lee
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Image Visibility Enhancement Under Inclement Weather with an Intensified Generative Training Set

Mathematics
Image-to-image translation inputs an image and transforms it into a new image. Deep learning-based image translation requires numerous training data to prevent overfitting; therefore, this study proposes a method to secure training data efficiently by ...
Se-Wan Lee, Seung-Hwan Lee, Dong-Min Son, Sung-Hak Lee   +3 more
doaj   +1 more source