Results 31 to 40 of about 44,616 (261)

Predicting lymph node recurrence in cT1‐2N0 tongue squamous cell carcinoma: collaboration between artificial intelligence and pathologists

The Journal of Pathology: Clinical Research
Researchers have attempted to identify the factors involved in lymph node recurrence in cT1‐2N0 tongue squamous cell carcinoma (SCC). However, studies combining histopathological and clinicopathological information in prediction models are limited.
Masahiro Adachi, Tetsuro Taki, Motohiro Kojima, Naoya Sakamoto, Kazuto Matsuura, Ryuichi Hayashi, Keiji Tabuchi, Shumpei Ishikawa, Genichiro Ishii, Shingo Sakashita   +9 more
doaj   +1 more source

Intraoral Rhabdomyosarcoma in a Young Boy

Journal of Indian Academy of Oral Medicine and Radiology, 2010
Rhabdomyosarcoma constitutes about 10 to 15% of the malignant neoplasms affecting children. Common sites of involvement include the head and neck, extremities and retropentoneum.
Aravinda Konidena, Manasi Kode
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

A Metal‐Phenolic Nanocluster Orchestrates Mito‐Ca2+ Metabolic Autonomy for Tumor Ca2+ Interference Therapy

Advanced Science, EarlyView.
Tumor Ca2+ interference therapy suffers from self‐protective Ca2+ metabolic autoregulation. In this scenario, a versatile metal‐phenolic nanocluster (TCMH) is engineered to modulate mitochondrial calcium uniporter (MCU) ‐mediated mito‐Ca2+ metabolic autonomy.
Ronglong Chen, Jia Huang, Yuepeng Wang, Shucong Yao, Fei Wu, Juan Liu, Chunxue Song, Li Lin, Xijun Lin, Yingjie Deng, Chao Zhang, Zhiquan Huang, Zixian Huang, Lisi Xie   +13 more
wiley   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

An Unusual Case of Sturge-Weber Syndrome with Squamous Cell Carcinoma of Tongue

Journal of Clinical and Diagnostic Research
Sturge-Weber Syndrome (SWS) is a rare congenital neurocutaneous syndrome affecting skin and soft tissues in the distribution of cranial nerve V, the ipsilateral cerebral hemisphere, and eye, with an incidence of 1 in 20,000 to 50,000 births, with no ...
Rajdeep Guha, Sukanya Naskar, Subhabrata Ghosh, Anannya Tripathy, Arnab Adak   +4 more
doaj   +1 more source

Evaluation of the Effect of Two Systemic Doses of HESA-A on Prevention of Induced Tongue Neoplasm in Rats

Journal of Dental Research, Dental Clinics, Dental Prospects, 2013
Background and aims. The aim of the present study was to compare the inhibitory effects of two systemic doses of HESA-A on prevention of 4-NQO-induced tongue neoplasms in rats. This study evaluated weight and histopathological changes.
Masoumeh Mehdipour, Ali Taghavi Zenouz, Mehran Mesgari Abbasi, Daryoush Mohajeri, Hossein Damghani, Sanaz Helli, Bita Abdollahi   +6 more
doaj   +1 more source

PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano‐Metabolic Symbiosis: E‐Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer

Advanced Science, EarlyView.
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu, Jiao Li, Juan Liu, Qi Dong, Haoyang Zhang, Yanjin Wang, Huibing Li, Ye Guan, Lei Cao, Manqing Zhang, Fangning Guo, Xue Liu, Zhen Yang, Mengmeng Lu, Hui Liu, Laiping Zhong, Tong Ji, Tingjiao Liu   +17 more
wiley   +1 more source

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

Advanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu, Yuanhe You, Yiyi Zhang, Yibin Dai, Xinyu Zhou, Yong Fu, Xi Lu, Yingying Huang, Zhihang Zhou, Ronghui Xia, Wutong Ju, Zhaoqi Yuan, Laiping Zhong, Tongchao Zhao   +13 more
wiley   +1 more source

The Pseudolesions of the Oral Mucosa: Differential Diagnosis and Related Systemic Conditions

Applied Sciences, 2019
Pseudolesions are defined as physiological or paraphysiological changes of the oral normal anatomy that can easily be misdiagnosed for pathological conditions such as potentially malignant lesions, infective and immune diseases, or neoplasms ...
Fedora della Vella, Dorina Lauritano, Carlo Lajolo, Alberta Lucchese, Dario Di Stasio, Maria Contaldo, Rosario Serpico, Massimo Petruzzi   +7 more
doaj   +1 more source