Results 41 to 50 of about 44,616 (261)

OTUD6A‐Mediated Deubiquitination of PRDX1 Protects Against Oral Ulcer by Restoring Mitochondrial Function

Advanced Science, EarlyView.
In human oral keratinocytes, OTUD6A promoted cell migration by deubiquitinating and stabilizing PRDX1. Conversely, OTUD6A deficiency reduced PRDX1 stability, triggering mitochondrial dysfunction and aggravating OU progression. ABSTRACT Oral ulcers (OU), as the most highly prevalent and recurrent oral mucosal lesion, have an unclear pathogenesis that ...
Xiaoyu Sun, Ruiwei Jia, Xingbei Pan, Rui Huang, Jiahong Chen, Ziyi Yao, Lei Yin, Jun Ma, Hongjieliang Wang, Xinyu Huang, Yilin Ma, Yifan Ping, Yuanyuan Chen, Huining Wang, Shengbin Huang, Guang Liang   +15 more
wiley   +1 more source

Giant tongue lipoma

Oral and Maxillofacial Surgery Cases, 2018
Lipomas are the most common soft tissue mesenchymal neoplasms are uncommon in the oral and maxillofacial region. Oral lipomas usually exhibit slow asymptomatic growth and are less than 20 mm at their largest diameter.
Yehya E.K. Gamie, Fazilet Bekiroglu, Simon N. Rogers   +2 more
doaj   +1 more source

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

The Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini, Nicola Montemurro, Ferdinando Paternostro, Immacolata Belviso, Massimo Galli, Petra Martini, Licia Uccelli, Jacopo Moggi‐Cecchi, Gregorio Oxilia   +8 more
wiley   +1 more source

Reconstrução microcirúrgica com retalho livre em forma de catedral após ressecção de carcinoma da língua: Relato de caso

Revista Brasileira de Cirurgia Plástica
As grandes lesões da língua representam um desafio significativo, que exige uma reconstrução tridimensional minuciosa para alcançar a ressecção oncológica e as funções ideais de fala e deglutição para o paciente.
Mario Augusto Ferrari de Castro, Kauê de Carvalho Moura, Bruno Pelinson Fogaça Duarte, Rogério Aparecido Dedivitis   +3 more
doaj   +1 more source

Epithelial-Myoepithelial Carcinoma of the Base of Tongue with Possible Lung Metastases

Case Reports in Otolaryngology, 2017
Background. Epithelial-myoepithelial carcinomas are rare neoplasms usually arising from the salivary glands. There is limited evidence in the literature on their prognosis in the base of the tongue but other cases have resolved without recurrence ...
Michael Y. Chen, Vipul Vyas, Ryan Sommerville   +2 more
doaj   +1 more source

Total Elbow Arthroplasty: Tips and Tricks in the Setting of Arthritis and Fracture Care

Arthroscopy Techniques, EarlyView.
Abstract The aim of this article is to illustrate our technique for total elbow arthroplasty, acknowledging the key technological advancements and evidence‐based techniques that have emerged in the last 2 decades. In this technical note, we describe our pearls for a reproducible and reliable total elbow arthroplasty procedure.
Benjamin Kerzner, Kyleen Jan, Alexander L. Hornung, John F. Hoy, Xavier C. Simcock   +4 more
wiley   +1 more source

Monitoring pharmacodynamic and molecular drug targets in liquid biopsy: Exploratory study in liver cancer with modelling of EGFR Receptor engagement

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Liquid biopsy is minimally invasive (compared with tissue biopsy) and has previously been used to generate systems data regarding drug elimination via hepatic enzymes and transporters. This study extends quantitative assessment of systems parameters in liquid biopsy to pharmacodynamic (PD) and disease markers relevant to cancer development
Zubida M. Al‐Majdoub, Armin Sepp, Amin Rostami‐Hodjegan, Brahim Achour   +3 more
wiley   +1 more source

Tongue gangrene and oropharyngeal carcinoma

Clinical and Biomedical Research, 2016
Gangrene of the tongue is a condition rarely described in the literature. It generally occurs in association with temporal arteritis and other vasculitides. We described a rare case of tongue necrosis associated with oropharyngeal carcinoma.
Fabio Muradás Girardi, Eduardo Lange Rech, Victória Teles França, Luiz Inácio Roman   +3 more
doaj   +2 more sources

Frequency of Cervical Nodal Metastasis in Early-Stage Squamous Cell Carcinoma of the Tongue

International Archives of Otorhinolaryngology, 2018
Introduction Oral cavity carcinoma is an aggressive tumor, with the tongue being one of the most common subsites of involvement. Surgery is a gold standard method of dealing with advanced-stage tumors.
Sadaf Qadeer Ahmed, Montasir Junaid, Sohail Awan, Maliha Kazi, Hareem Usman Khan, Sohail Halim   +5 more
doaj   +1 more source

NMDAR‐antibody encephalitis: Seizure semiology and EEG findings

Epileptic Disorders, EarlyView.
Abstract Background N‐methyl‐D‐aspartate receptor antibody encephalitis (NMDAR‐Ab‐E) is an autoantibody‐mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability. Objectives To describe acute seizure semiology and electroencephalogram (EEG) findings in patients with a ...
Maria Emilia C. Andraus, Bernard Liem, Sidra Aurangzeb, Mkael Symmonds, Adam E. Handel, Sarosh R. Irani, Arjune Sen   +6 more
wiley   +1 more source