Results 51 to 60 of about 27,403 (299)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
PLoS ONE, 2020 Near-infrared transillumination is used in the diagnosis and the management of different eye diseases. In particular, it enables the visualization of melanin in the pigment epithelium of the iris.
Maciej Czepita
doaj +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
Tonic Pupil Following Pars Plana Vitrectomy and Endolaser
Case Reports in Medicine, 2009 Tonic pupil was observed in a 67 year-old patient following a retinal detachment repair with pars plana vitrectomy, endolaser and silicone oil tamponade performed under retrobulbar anesthesia.
Benyamin Ebrahim +3 more
doaj +1 more source
Journal of Clinical Ophthalmology and Research, 2020 Adie’s pupil, also called as Adie’s tonic pupil is the common cause of anisocoria or unequal pupils in clinics. It is used to denote the parasympathetic denervation of the pupil with absent light responses and retained near reflex.
Sowmya Raveendra Murthy
doaj +1 more source
Tonic pupils from giant cell arteritis [PDF]
British Journal of Ophthalmology, 2003 The tonic pupil is characterised by poor reactivity to light, a slow tonic constriction and redilation to a near target, and supersensitivity to topical dilute pilocarpine.1 Most instances do not have an identifiable cause; however, a variety of conditions including herpes zoster, orbital trauma including surgery, and paraneoplastic syndromes may ...
R, Foroozan +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Isolated dilated pupil: Is it adie's pupil?
Archives of Medicine and Health Sciences, 2016 Adie's tonic pupil, though well known in literature is a rarity in practice. Few case reports have mentioned the occurrence of Adie's pupil during a migraine attack.
Uma Sinharoy +3 more
doaj +1 more source
, 2012 Leon Battista Alberti and Marsilio Ficino, though separated by twenty-nine years in age, had a close relationship as mentor and pupil. Concepts which can be found in Alberti’s De pictura (1435) and De re aedificatoria (1450) are infused in Ficino’s De ...
Hendrix, John S
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source