Results 81 to 90 of about 1,607 (175)

Tinnitus does not require Macroscopic Tonotopic Map Reorganization

open access: yesFrontiers in Systems Neuroscience, 2012
The pathophysiology underlying tinnitus, a hearing disorder characterized by the chronic perception of phantom sound, has been related to aberrant plastic reorganization of the central auditory system.
Dave R.M. Langers   +5 more
doaj   +1 more source

Representation of lateralization and tonotopy in primary versus secondary human auditory cortex

open access: yesNeuroImage, 2007
Functional MRI was performed to investigate differences in the basic functional organization of the primary and secondary auditory cortex regarding preferred stimulus lateralization and frequency. A modified sparse acquisition scheme was used to spatially map the characteristics of the auditory cortex at the level of individual voxels.
Langers, Dave R. M.   +2 more
openaire   +3 more sources

Irx3/5 Null Deletion in Mice Blocks Cochlea‐Saccule Segregation and Disrupts the Auditory Tonotopic Map

open access: yesJournal of Comparative Neurology, Volume 532, Issue 12, December 2024.
Deletion mutant of Irx3/5 shows the cochlear base fused with the saccule, whereas in wild‐type mice, the saccule is separated from the base by the ductus reuniens. Irx3 and Irx5 are potential evolutionary branch‐point genes necessary for balance‐sound segregation.
Bernd Fritzsch   +7 more
wiley   +1 more source

Cerebral blood volume sensitive layer-fMRI in the human auditory cortex at 7T: Challenges and capabilities.

open access: yesPLoS ONE, 2023
The development of ultra high field fMRI signal readout strategies and contrasts has led to the possibility of imaging the human brain in vivo and non-invasively at increasingly higher spatial resolutions of cortical layers and columns.
Lonike K Faes   +2 more
doaj   +1 more source

Magnetic Force Nanoprobe for Direct Observation of Audio Frequency Tonotopy of Hair Cells

open access: yesNano Letters, 2016
Sound perception via mechano-sensation is a remarkably sensitive and fast transmission process, converting sound as a mechanical input to neural signals in a living organism. Although knowledge of auditory hair cell functions has advanced over the past decades, challenges remain in understanding their biomechanics, partly because of their biophysical ...
Ji-Wook, Kim   +6 more
openaire   +3 more sources

Metabolic Profiling of Cochlear Organoids Identifies α‐Ketoglutarate and NAD+ as Limiting Factors for Hair Cell Reprogramming

open access: yesAdvanced Science, Volume 11, Issue 34, September 11, 2024.
Regeneration of cochlear hair cells holds great promise for hearing restoration. Cochlear organoids have emerged as valuable system for high throughput analyses of mammalian hair cell development. This study suggests that metabolic decoupling is an underlying barrier for efficient hair cell regeneration, and points to the roles of key metabolites such ...
Qing Liu   +10 more
wiley   +1 more source

Microanatomy of the human tunnel of Corti structures and cochlear partition‐tonotopic variations and transcellular signaling

open access: yesJournal of Anatomy, Volume 245, Issue 2, Page 271-288, August 2024.
Mid‐modiolar semi‐thin section of a human cochlea with tonotopic estimates based on synchrotron 3‐D imaging. Abstract Auditory sensitivity and frequency resolution depend on the optimal transfer of sound‐induced vibrations from the basilar membrane (BM) to the inner hair cells (IHCs), the principal auditory receptors.
Dina Giese   +9 more
wiley   +1 more source

An anatomical and functional topography of human auditory cortical areas

open access: yesFrontiers in Neuroscience, 2014
While advances in magnetic resonance imaging (MRI) throughout the last decades have enabled the detailed anatomical and functional inspection of the human brain non-invasively, to date there is no consensus regarding the precise subdivision and ...
Michelle eMoerel   +7 more
doaj   +1 more source

The Neural Representation of Binaural Sound Localization Cues Across Different Subregions of the Chicken's Inferior Colliculus

open access: yesJournal of Comparative Neurology, Volume 532, Issue 7, July 2024.
This study matched physiology and anatomical subregions in the chicken inferior colliculus. We found neural topographies for binaural sound localization cues, but, in contrast to the well‐studied barn owl, there was no distinct differentiation of responses in the different subregions.
Roberta Aralla   +2 more
wiley   +1 more source

Tonotopic Organization of the Hyperpolarization-activated Current (Ih) in the Mammalian Medial Superior Olive

open access: yesFrontiers in Neural Circuits, 2013
Neuronal membrane properties can largely vary even within distinct morphological cell classes. The mechanisms and functional consequences of this diversity, however, are little explored.
Veronika eBaumann   +5 more
doaj   +1 more source

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