Results 121 to 130 of about 10,706,028 (311)
OCIS Public Goods Tool Development [PDF]
There has recently been an increase in interest amongst policy-makers in the question of whether farming provides a “public good” beyond the simple production of food, which justifies support from, for instance, EU agricultural policy.
Cooper, Nick +6 more
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Thermal performance enhancement in a solar air heater fitted with flapped V-baffles: Numerical study
Considering solar energy equipment, a solar air heater is an engineering equipment that is widely used today. To get the most benefit from energy use, thermal performance enhancement of the equipment is very important.
Chinnapat Turakarn +2 more
doaj +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Dalam menentukan kualitas sesuatu diperlukan beberapa metode untuk menentukan standar. Cara yang sering digunakan dewasa ini yaitu tujuh alat termasuk untuk menentukan keputusan. Saat ini telah berkembang pula metode untuk mengambil keputusan dalam menentukan kualitas yaitu salah satu contohnya Delphi.
openaire +2 more sources
Homo heidelbergensis: The Tool to Our Success [PDF]
Homo heidelbergensis, a physiological variant of the species Homo sapien, is an extinct species that existed in both Europe and parts of Asia from 700,000 years ago to roughly 300,000 years ago (carbon dating). This “subspecies” of Homo sapiens, as it is
Burkard, Alexander
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Communication strategy tool user guide [PDF]
The application of Cradle to Cradle (C2C) principles in business sites is likely to be hampered by several barriers, some of which are socio-cultural in nature. To promote change and new thinking in the way business sites are designed, built and operated,
Ankrah, NA, Manu, E
core

