Results 131 to 140 of about 10,823,317 (311)
, 2017 Dalam menentukan kualitas sesuatu diperlukan beberapa metode untuk menentukan standar. Cara yang sering digunakan dewasa ini yaitu tujuh alat termasuk untuk menentukan keputusan. Saat ini telah berkembang pula metode untuk mengambil keputusan dalam menentukan kualitas yaitu salah satu contohnya Delphi.
openaire +2 more sources
OCIS Public Goods Tool Development [PDF]
, 2011 There has recently been an increase in interest amongst policy-makers in the question of whether farming provides a “public good” beyond the simple production of food, which justifies support from, for instance, EU agricultural policy.
Cooper, Nick +6 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Thermal performance enhancement in a solar air heater fitted with flapped V-baffles: Numerical study
Case Studies in Thermal EngineeringConsidering solar energy equipment, a solar air heater is an engineering equipment that is widely used today. To get the most benefit from energy use, thermal performance enhancement of the equipment is very important.
Chinnapat Turakarn +2 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
SCOF: A Standardised, Customisable Online Feedback Tool [PDF]
, 2012 Increasing pressures on staff, combined with increased requests for feedback from students mean that there is less time to do more things. Investigation into potential methods to assist the staff of the School of Engineering and Mathematical Sciences at ...
Glover, I.
core
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source