Results 111 to 120 of about 5,252,997 (308)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Quantifying the Quality of Web-Based Health Information on Student Health Center Websites Using a Software Tool: Design and Development Study. [PDF]

JMIR Form Res, 2022
Kulkarni A, Wong M, Belsare T, Shah R, Yu Yu D, Coskun B, Holschuh C, Kakar V, Modrek S, Smirnova A.   +9 more
europepmc   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Ergonomic Design of Shovel to Improve Productivity in Sorghum Silage Industry

Industria: Jurnal Teknologi dan Manajemen Agroindustri
Sorghum silage production is an important process in the animal feed industry. However, manually transferring chopped sorghum with existing shovels can increase workers' risk of musculoskeletal disorders. This study aimed to design an ergonomic shovel to
Dino Caesaron, Farell Ardani, Yudistira, Ilma Mufidah   +3 more
doaj   +1 more source

Design and validation of a tool to assess the safety principles of working with nanomaterials in nanotechnology laboratories

طب کار, 2021
Introduction: The unique properties of nanomaterials, in addition to their applications in science and technology, can be a threat to human health and the environment. Exposure to these materials may occur in workplaces or in research laboratories.
Soqrat Omari Shekaftik, Saeed Mohammadi, MoradAli Zareipour, Azad Haghighi Asl, raziyeh Soltani Gerdefaramarzi, Fakhradin Ahmadi Kanrash   +5 more
doaj  

High Tea at the Conviviality Café: Research Tool or Design Intervention? [PDF]

, 2013
The FLEX project asked how we might age convivially at home. In response to concerns about an ageing British population, we looked at social factors of wellbeing in the ambient realm of neighbourhood encounters.
Bond, Lowri, Botten, Carol, Light, Ann, McIntosh, Linsey, Milligan, Andy   +4 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Designing Design Tools

, 2017
Mainstream digital graphic design tools seldom evolved since their creation, more than 25 years ago. In this dissertation, I address the following questions: How do designers work with design software? And how can we design novel design tools that better support designer practices?
openaire   +1 more source

Learning Design Tools

, 2006
In this chapter we provide an overview of the tools required for working with the Learning Design specification (LD 2003). These include editors for creating Units of Learning (UOLs), runtime players, and repositories for storing UOLs. We first examine the context provided by the Valkenburg Group Reference Architecture, identifying those parts which ...
Griffiths, David, Blat, Josep, Garcia, Rocío, Vogten, Hubert, Kwong, KL   +4 more
openaire   +1 more source

A knowledge-based system design/information tool [PDF]

The objective of this effort was to develop a Knowledge Capture System (KCS) for the Integrated Test Facility (ITF) at the Dryden Flight Research Facility (DFRF). The DFRF is a NASA Ames Research Center (ARC) facility. This system was used to capture the
Allen, James G., Sikora, Scott E.
core   +1 more source