Results 81 to 90 of about 1,308,345 (265)

Experimental Investigation of the Effects of Coolant Temperature on Cutting Tool Wear in the Machining Process

Machines
In machining processes, the heat generated in the cutting zone varies depending on cutting parameters such as depth of cut, cutting speed and feed rate.
Osman Şahin, Durmuş Karayel, Mustafa Ali Ertürk, Ergün Nart, Ömer Seçgin   +4 more
doaj   +1 more source

Explainable Remaining Tool Life Prediction for Individualized Production Using Automated Machine Learning. [PDF]

Sensors (Basel), 2023
Krupp L, Wiede C, Friedhoff J, Grabmaier A.   +3 more
europepmc   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Investigation of Tool Wear and Tool Life Modelling

Engineering review, 2004
According to the ISO 3685 standard by adopting a previously chosen tool wear criterion, the tool life is obtained from experimental data which report monitoring of the tool's flank wear progression at discrete machining times. Thus, the data collected along the tool wear tests are not fully exploited. In this paper a new approach to tool life modelling
Paliska, Davor, Cukor, Goran
openaire   +2 more sources

Effect of Cutting Fluid on Milled Surface Quality and Tool Life of Aluminum Alloy. [PDF]

Materials (Basel), 2023
Pang S, Zhao W, Qiu T, Liu W, Yan P, Jiao L, Wang X.   +6 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Investigations on the machinability performance of Al2O3/TiCN CVD coated carbide tools in sustainable high-speed hard-turning of AISI 4340 alloy steel

Materials Research Express
This study investigates the effectiveness of CVD coated carbide inserts in turning hardened AISI 4340 steel at high-machining speed V = 300, 350 m min ^−1 under sustainable dry cutting environment.
Nabil Jouini, Saima Yaqoob, Jaharah A Ghani   +2 more
doaj   +1 more source

Design and Implementation of Machine Tool Life Inspection System Based on Sound Sensing. [PDF]

Sensors (Basel), 2022
Liu TH, Chi JZ, Wu BL, Chen YS, Huang CH, Chu YS.   +5 more
europepmc   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source