Results 81 to 90 of about 9,039,965 (305)

Concept of Integrating a Hybrid Thermal Error Compensation Into an Existing Machine Tool Control Architecture

Journal of Machine Engineering
Thermal error compensation via a numeric control (NC) system is a proven option for upgrading the precision of machine tools. The main advantage is the generally cost-effective application, as no changes to the machine design are necessary. Since modern
Alexander Geist, Muhammad Faisal Yaqoob, Christian Friedrich, Christian Naumann, Steffen Ihlenfeldt   +4 more
doaj   +1 more source

Predictive Technology Assessment by Means of a Structure-Based Method of Machine Learning

Journal of Machine Engineering, 2020
From a user perspective, the current development of the generic term Industry 4.0 increasingly moves its orientation towards flexible production. Due to increasingly variable products with small quantities and the resulting high degree of adaptability of
Manja Mai-Ly PFAFF, Uwe FRIEß, Andreas OTTO, Matthias PUTZ   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Object-oriented Tools for Distributed Computing [PDF]

, 1993
Distributed computing systems are proliferating, owing to the availability of powerful, affordable microcomputers and inexpensive communication networks.
Adler, Richard M.
core   +1 more source

Investigation of Tool Cooling and Heat Transfer Using Computational Fluid Dynamics Simulations

Journal of Machine Engineering
Thermal errors remain one of the biggest challenges for the precision of cutting machine tools. Aside from optimizations in the machine tool design and behaviour, optimal cutting process parameters and targeted usage of cutting fluid or alternative ...
Christian Naumann, Claus-Dieter Schmidt, Alexander Geist, Steffen Brier, Janine Glanzel, Philipp Klimant, Steffen Ihlenfeldt, Martin Dix   +7 more
doaj   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Z Unification Tools in Generic Formaliser [PDF]

, 1997
We describe some prototype tools for performing unification (i.e. deriving the least common refinement) of simple Z specifications. The techniques used are those described in http://alethea.ukc.ac.uk/Dept/Computing/Research/NDS/consistency/cccfpsiZ.html ...
Boiten, Eerke Albert
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source