BMP9-initiated osteogenic/odontogenic differentiation of mouse tooth germ mesenchymal cells (TGMCS) requires Wnt/β-catenin signalling activity. [PDF]
J Cell Mol Med, 2021 Luo W +20 more
europepmc +2 more sources
The effect of Prrx2 on the development of mouse molar germ
Kouqiang hemian waike zazhi, 2023 [Objective:] To investigate the expression level of paired related homeobox 2 (Prrx2) at different stages of mouse molar germ and its effect on molar germ development.
ZHU Zhewen +3 more
doaj +1 more source
mTORC1 signaling pathway regulates tooth repair
International Journal of Oral Science, 2023 Tooth germ injury can lead to abnormal tooth development and even tooth loss, affecting various aspects of the stomatognathic system including form, function, and appearance.
Honghong Liu +9 more
doaj +1 more source
Prevention of the disrupted enamel phenotype in Slc4a4-null mice using explant organ culture maintained in a living host kidney capsule. [PDF]
, 2014 Slc4a4-null mice are a model of proximal renal tubular acidosis (pRTA). Slc4a4 encodes the electrogenic sodium base transporter NBCe1 that is involved in transcellular base transport and pH regulation during amelogenesis.
Kurtz, Ira, Paine, Michael L, Wen, Xin
core +12 more sources
Scientific Reports, 2023 Recent advances in regenerative technology have made the regeneration of various organs using pluripotent stem cells possible. However, a simpler screening method for evaluating regenerated organs is required to apply this technology to clinical ...
Tomomi Yuta +11 more
doaj +1 more source
Overburdened ferroptotic stress impairs tooth morphogenesis
eLife, 2023 The role of regulated cell death in organ development, particularly the impact of non-apoptotic cell death, remains largely uncharted. Ferroptosis, a non-apoptotic cell death pathway known for its iron dependence and lethal lipid peroxidation, is ...
Haisheng Wang +5 more
doaj +1 more source
Eruption of Bioengineered Teeth: A New Approach Based on a Polycaprolactone Biomembrane
Nanomaterials, 2021 Obtaining a functional tooth is the ultimate goal of tooth engineering. However, the implantation of bioengineered teeth in the jawbone of adult animals never allows for spontaneous eruption due mainly to ankylosis within the bone crypt. The objective of
Céline Stutz +7 more
doaj +1 more source
Talon cusp affecting primary dentition in two siblings: a case report [PDF]
, 2014 The term talon cusp refers to a rare developmental dental anomaly characterized by a cusp-like structure projecting from the cingulum area or cement-enamel junction.
King, N. M. +3 more
core +1 more source
Gestational protein restriction alters the RANKL/OPG system in the dental germ of offsprings
Journal of Oral Biology and Craniofacial Research, 2020 Objective: Evaluate the dentinogenesis in the offspring of rats submitted to gestational protein restriction (GPR). Design: The offspring were evaluated at the 21st day of gestation (21 dG). Assessments were made of morphological parameters and the RANKL/
Bruno Calsa +4 more
doaj +1 more source
Role of Cell Death in Cellular Processes During Odontogenesis
Frontiers in Cell and Developmental Biology, 2021 The development of a tooth germ in a precise size, shape, and position in the jaw, involves meticulous regulation of cell proliferation and cell death.
John Abramyan +5 more
doaj +1 more source