Results 1 to 10 of about 10,608 (245)

Role of Cell Death in Cellular Processes During Odontogenesis

Frontiers in Cell and Developmental Biology, 2021
The development of a tooth germ in a precise size, shape, and position in the jaw, involves meticulous regulation of cell proliferation and cell death.
Poongodi Geetha-Loganathan, Marie Šulcová, Marcela Buchtova   +2 more
exaly   +4 more sources

MicroRNA-enriched small extracellular vesicles possess odonto-immunomodulatory properties for modulating the immune response of macrophages and promoting odontogenesis

Stem Cell Research and Therapy, 2020
Background To investigate the odonto-immunomodulatory properties of dental pulp stem cell-derived small extracellular vesicles (DPSCs-sEV), which promote odontogenesis by switching macrophages toward the pro-healing M2 phenotype.
Jianmao Zheng, Xiaoli Hu
exaly   +3 more sources

Spatial and temporal gene expression patterns during early human odontogenesis process

Frontiers in Bioengineering and Biotechnology
Studies on odontogenesis are of great importance to treat dental abnormalities and tooth loss. However, the odontogenesis process was poorly studied in humans, especially at the early developmental stages.
Yejia Yu, Kun Wang, Zhuo Wang, Haoyang Cai, Chengcheng Liao, Yutao Wu, Jingyi Zhang, Weidong Tian, Li Liao   +8 more
exaly   +4 more sources

Odontogenesis-related developmental microenvironment facilitates deciduous dental pulp stem cell aggregates to revitalize an avulsed tooth

Biomaterials, 2021
Harnessing developmental processes for tissue engineering represents a promising yet challenging approach to regenerative medicine. Tooth avulsion is among the most serious traumatic dental injuries, whereas functional tooth regeneration remains ...
Hao Guo, Bei Li, Xiaoning He
exaly   +2 more sources

Molecular insight into odontogenesis in hyperglycemic environment: A systematic review

Journal of Pharmacy and Bioallied Sciences, 2020
Diabetes mellitus is an endocrinal disorder affecting worldwide and the disease incidence is rising alarmingly high. The effects of diabetes on tooth development are explored by limited studies and their molecular insights are very rarely studied.
Andamuthu Yamunadevi, Ramani Pratibha, Muthusamy Rajmohan, Nalliappan Ganapathy, Jeyachandran Porkodisudha, Dhanasing Pavithrah, Sengottaiyan Mahendraperumal   +6 more
doaj   +2 more sources

Odontogenesis and neuronal differentiation characteristics of periodontal ligament stem cells from beagle dog

Journal of Cellular and Molecular Medicine, 2020
Periodontal ligament stem cells (PDLSCs) from beagle dogs had the characteristics of multi‐directional differentiation and had great application potential in tissue engineering and cell regenerative medicine.
Xiaojie Li, Dapeng Liao, Gang Sun
exaly   +2 more sources

Sonic Hedgehog Signaling and Development of the Dentition [PDF]

Journal of Developmental Biology, 2017
Sonic hedgehog (Shh) is an essential signaling peptide required for normal embryonic development. It represents a highly-conserved marker of odontogenesis amongst the toothed vertebrates.
Maisa Seppala, Gareth J. Fraser, Anahid A. Birjandi, Guilherme M. Xavier, Martyn T. Cobourne   +4 more
doaj   +3 more sources

Polydopamine-coated bioactive glass for immunomodulation and odontogenesis in pulpitis

Materials Today Bio
Preserving vital pulp in cases of dental pulpitis is desired but remains challenging. Previous research has shown that bioactive glass (BG) possesses notable capabilities for odontogenic differentiation.
Jilin Wu, Yan-Mei Dong
exaly   +2 more sources

Role of Primary Cilia in Odontogenesis [PDF]

Journal of Dental Research, 2017
Primary cilium is a solitary organelle that emanates from the surface of most postmitotic mammalian cells and serves as a sensory organelle, transmitting the mechanical and chemical cues to the cell. Primary cilia are key coordinators of various signaling pathways during development and maintenance of tissue homeostasis.
M, Hampl, P, Cela, H L, Szabo-Rogers, M, Kunova Bosakova, H, Dosedelova, P, Krejci, M, Buchtova   +6 more
openaire   +3 more sources

Mesoporous Bioactive Glass Nanoparticles Promote Odontogenesis and Neutralize Pathophysiological Acidic pH

Frontiers in Materials, 2020
Pathophysiological acidic-pH hinders the dental biomaterial-based pulp-dentin regeneration. Bioactive glass (BG) synthesized by sol-gel methods had shown odontogenic and pulp regeneration potential.
Wenyan Huang, Jingjing Yang, Qiong Feng, Yan Shu, Yan Shu, Cong Liu, Shihan Zeng, Hongbing Guan, Lihong Ge, Lihong Ge, Janak L. Pathak, Sujuan Zeng   +11 more
doaj   +2 more sources