Role of Cell Death in Cellular Processes During Odontogenesis
Frontiers in Cell and Developmental Biology, 2021 The development of a tooth germ in a precise size, shape, and position in the jaw, involves meticulous regulation of cell proliferation and cell death.
Poongodi Geetha-Loganathan +2 more
exaly +3 more sources
Spatial and temporal gene expression patterns during early human odontogenesis process
Frontiers in Bioengineering and BiotechnologyStudies on odontogenesis are of great importance to treat dental abnormalities and tooth loss. However, the odontogenesis process was poorly studied in humans, especially at the early developmental stages.
Haoyang Cai +2 more
exaly +3 more sources
Genetic architecture of craniofacial morphogenesis: roles of PAX3, PAX7, and PAX9 [PDF]
Frontiers in Cell and Developmental BiologyCraniofacial morphogenesis is a highly coordinated developmental process governed by complex genetic and molecular interactions. Among these, the PAX family of transcription factors plays a pivotal role in the regulation of neural crest specification ...
Kun Wang +12 more
doaj +2 more sources
The metamorphic transition of the frog mouth: from tadpole keratinized mouthparts to adult teeth [PDF]
Royal Society Open ScienceTeeth have been a prominent feature of most vertebrates for 400 million years, and the core regulatory network underlying embryonic tooth formation is deeply conserved.
Daniel J. Paluh +6 more
doaj +2 more sources
Role of Primary Cilia in Odontogenesis [PDF]
Journal of Dental Research, 2017 Primary cilium is a solitary organelle that emanates from the surface of most postmitotic mammalian cells and serves as a sensory organelle, transmitting the mechanical and chemical cues to the cell. Primary cilia are key coordinators of various signaling pathways during development and maintenance of tissue homeostasis.
Marek Hampl +6 more
openalex +3 more sources
Expression and Function of NUMB in Odontogenesis [PDF]
BioMed Research International, 2013 NUMB is a multifunctional protein implicated to function in self-renewal and differentiation of progenitors in several tissues. To characterize the transcripts and to analyze the expression pattern of NUMB in odontogenesis, we isolated 2 full-length clones for NUMB from mouse dental pulp mRNA.
Haitao Li +6 more
openalex +3 more sources
Fibronectin-gelatin nanofilm coating improves dental pulp stem cell survival and differentiation in odontogenesis-mimicking organotypic 3D bilayered constructs. [PDF]
Front Dent MedJimenez-Armijo A +8 more
europepmc +3 more sources
p75NTR Promotes Circadian-Driven Mineralization During Tooth Development via CK2/PER2 Pathway. [PDF]
Cell ProlifThe diagram illustrates how the circadian rhythm regulates the p75NTR‐CK2‐PER2 axis, driving rhythmic biomineralisation during tooth development. ABSTRACT Circadian rhythm is an essential biological process that synchronises physiological activities with environmental light/dark cycles.
Zhao M +8 more
europepmc +2 more sources
Impact of FasL Stimulation on Sclerostin Expression and Osteogenic Profile in IDG-SW3 Osteocytes
Biology, 2021 The Fas ligand (FasL) is known from programmed cell death, the immune system, and recently also from bone homeostasis. As such, Fas signalling is a potential target of anti-osteoporotic treatment based on the induction of osteoclastic cell death.
Adela Kratochvilova +6 more
doaj +1 more source
Tissue-Engineered Odontogenesis
Journal of Hard Tissue Biology, 2005 In this study, we have developed a tooth regeneration model derived from mouse tooth germ cells based on tissue engineering. Lower first molars from DDY mice embryos at E 14 were used. Biodegradable Polyglycolate acid (PGA) scaffolds were fabricated, seeded with dissociated the first molars cells, and implanted into the subcapsular layer of kidney in ...
Shinji Iwatsuki +3 more
openalex +3 more sources