Results 11 to 20 of about 10,627 (262)

Piezo1 Regulates Odontogenesis via a FAM83G-Mediated Mechanism in Dental Papilla Cells In Vitro and In Vivo [PDF]

Biomolecules
This study explored the role of Piezo1 in the odontogenic differentiation of dental papilla cells (DPCs) and tissue, focusing on a mechanism involving family with sequence similarity 83, member G (FAM83G). Here, we found Piezo1, a mechanosensitive cation
Xinyue Sheng, Jingzhou Li, Haozhen Ma, Hongwen He, Qin Liu, Shilin Jia, Fuping Zhang, Fang Huang   +7 more
doaj   +2 more sources

The metamorphic transition of the frog mouth: from tadpole keratinized mouthparts to adult teeth [PDF]

Royal Society Open Science
Teeth have been a prominent feature of most vertebrates for 400 million years, and the core regulatory network underlying embryonic tooth formation is deeply conserved.
Daniel J. Paluh, Madeline Brinkman, Kyliah Gilliam-Beale, Daniela Salcedo-Recio, Jacob Szafranski, James Hanken, Gareth J. Fraser   +6 more
doaj   +2 more sources

Cathepsin K‐Positive Cell Lineage Promotes In Situ Dentin Formation Controlled by Nociceptive Sonic Hedgehog [PDF]

Advanced Science
Oral diseases affect nearly half of the global population throughout their lifetime causing pain, as estimated by the World Health Organization. Preservation of vital pulp is the therapeutic core as well as a challenge to protect natural teeth.
Ruoshi Xu, Xiaohan Zhang, Weimin Lin, Yushun Wang, Danting Zhang, Shuang Jiang, Linfeng Liu, Jiaying Wang, Xutao Luo, Xiao Zhang, Junjun Jing, Quan Yuan, Chenchen Zhou   +12 more
doaj   +2 more sources

Impact of FasL Stimulation on Sclerostin Expression and Osteogenic Profile in IDG-SW3 Osteocytes

Biology, 2021
The Fas ligand (FasL) is known from programmed cell death, the immune system, and recently also from bone homeostasis. As such, Fas signalling is a potential target of anti-osteoporotic treatment based on the induction of osteoclastic cell death.
Adela Kratochvilova, Alice Ramesova, Barbora Vesela, Eva Svandova, Herve Lesot, Reinhard Gruber, Eva Matalova   +6 more
doaj   +1 more source

Ectopic premolar tooth in the sigmoid notch [PDF]

, 2016
Impaction of a mandibular premolar is relatively uncommon. Ectopic placement is more unusual and there has been no discussion in the literature of an ectopic mandibular premolar in the coronoid process. In this case report, we present an impacted ectopic
Akgul, Hayati Murat, Bayrakdar, Ibrahım Sevki, Torenek, Kubra   +2 more
core   +13 more sources

Genome-wide identification of potential odontogenic genes involved in the dental epithelium-mesenchymal interaction during early odontogenesis

BMC Genomics, 2023
Background Epithelium-mesenchymal interactions are involved in odontogenic processes. Previous studies have focused on the intracellular signalling regulatory network in tooth development, but the functions of extracellular regulatory molecules have ...
Jiawen Chen, T. Sun, Yan You, B. Lin, Buling Wu, Jingyi Wu   +5 more
semanticscholar   +1 more source

A novel mutation of SATB2 inhibits odontogenesis of human dental pulp stem cells through Wnt/β-catenin signaling pathway

Stem cell research & therapeutics, 2021
SATB2-associated syndrome (SAS) is a multisystem disorder caused by mutation of human SATB2 gene. Tooth agenesis is one of the most common phenotypes observed in SAS.
T. Xin, Qian Li, Rushui Bai, Ting Zhang, Yanheng Zhou, Yuehua Zhang, B. Han, Ruili Yang   +7 more
semanticscholar   +1 more source

Formation and Developmental Specification of the Odontogenic and Osteogenic Mesenchymes

Frontiers in Cell and Developmental Biology, 2020
Within the mandible, the odontogenic and osteogenic mesenchymes develop in a close proximity and form at about the same time. They both originate from the cranial neural crest. These two condensing ecto-mesenchymes are soon separated from each other by a
Eva Svandova, Renata Peterkova, Eva Matalova, Eva Matalova, Herve Lesot   +4 more
doaj   +1 more source

Immunomodulation stimulates the innervation of engineered tooth organ [PDF]

, 2014
The sensory innervation of the dental mesenchyme is essential for tooth function and protection. Sensory innervation of the dental pulp is mediated by axons originating from the trigeminal ganglia and is strictly regulated in time. Teeth can develop from
Bécavin, Thibault, Keller, Laetitia, Kuchler-Bopp, Sabine, Kökten, Tunay, Lesot, Hervé, Weikert, Jean-Luc   +5 more
core   +13 more sources

Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor

Frontiers in Cell and Developmental Biology, 2023
As the dentition forms and becomes functional, the alveolar bone is remodelled. Metalloproteinases are known to contribute to this process, but new regulators are emerging and their contextualization is challenging.
S. Varadinkova, S. Varadinkova, V. Oralova, V. Oralova, M. Clarke, J. Frampton, L. Knopfova, L. Knopfova, H. Lesot, P. Bartos, E. Matalova, E. Matalova   +11 more
doaj   +1 more source