Results 41 to 50 of about 5,910 (225)

Odontogenic Effect of Icariin on the Human Dental Pulp Cells

open access: yesMedicina, 2022
Background and Objectives: Human dental pulp cells (HDPCs) can be used for dentin regeneration due to its odontogenic differentiation property. Icariin can induce osteogenic differentiation of stem cells.
Guo Liu   +4 more
doaj   +1 more source

Endodontic approach in a replanted tooth with an immature root apex and chronic apical periodontitis: a case report [PDF]

open access: yesRestorative Dentistry & Endodontics, 2020
This study describes the clinical steps taken in the treatment of a patient who had an avulsed right upper central incisor that presented with incomplete root development and chronic apical periodontitis.
Graziela Garrido Mori   +2 more
doaj   +1 more source

Single‐Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis

open access: yesCell Proliferation, EarlyView.
STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Yanfei Zhu   +12 more
wiley   +1 more source

Dens Invaginatus as a Biomechanical Risk Modifier in Dental Trauma: Finite Element Analysis

open access: yesDental Traumatology, EarlyView.
ABSTRACT Introduction/Aims Traumatic dental injuries are common in childhood and may adversely affect functional and psychosocial well‐being. Dens invaginatus, a developmental anomaly caused by the infolding of the enamel organ during odontogenesis, alters tooth morphology and may influence biomechanical behavior under traumatic loading.
Emine Şuranur Ayaz   +6 more
wiley   +1 more source

Optimal Hypoxia Mimetic Small Molecules for Enhancing Angiogenic Properties of Stem Cells From Human Exfoliated Deciduous Teeth

open access: yesInternational Endodontic Journal, EarlyView.
ABSTRACT Aim Hypoxic preconditioning of cells holds promise for regenerative therapies, yet identifying effective and safe methods for clinical application remains challenging. We aimed to determine optimal hypoxia‐mimetic small molecules (SMs) that stabilize hypoxia‐inducible factor‐1α (HIF‐1α) and their dosages for hypoxic preconditioning in stem ...
Hong Wang   +9 more
wiley   +1 more source

Spatiotemporal Expression Patterns of Critical Genes Involved in FGF Signaling during Morphogenesis and Odontogenesis of Deciduous Molar in Miniature Pig [PDF]

open access: green, 2021
Wenwen Guo   +8 more
openalex   +1 more source

A description of dental microanatomy and implantation geometry in Chamaeleonidae

open access: yesJournal of Anatomy, EarlyView.
A reassessment of the dental histology in adult chamaeleons reveals the presence of periodontal ligament. Alongside alveolar bone and cementum, these tissues together constitute a compacted and remodelled tripartite periodontium. Our findings include the novel observation of plicidentine‐like protuberances of dentine within underlying bone.
Giles D. Sukkert   +4 more
wiley   +1 more source

Mesoporous Bioactive Glass Nanoparticles Promote Odontogenesis and Neutralize Pathophysiological Acidic pH

open access: yesFrontiers in Materials, 2020
Pathophysiological acidic-pH hinders the dental biomaterial-based pulp-dentin regeneration. Bioactive glass (BG) synthesized by sol-gel methods had shown odontogenic and pulp regeneration potential.
Wenyan Huang   +11 more
doaj   +1 more source

MiR-335-3p/miR-155-5p Involved in IGFBP7-AS1–Enhanced Odontogenic Differentiation

open access: yesInternational Dental Journal, 2023
Background: The differentiation of stem cells from exfoliated deciduous teeth (SHEDs) into odontoblasts determines the regeneration of dentin-pulp complex. Non-coding RNAs (ncRNAs), including microRNA (miRNA) and long non-coding RNA (lncRNA), participate
Ningxin Zhu   +4 more
doaj   +1 more source

Stem Cells From Dental Pulp, Periodontal Tissues, and Other Oral Sources: Biological Concepts and Regenerative Potential

open access: yesJournal of Periodontal Research, EarlyView.
A graphical abstract recapping the different sources of dental, periodontal, and other oral‐derived mesenchymal stromal cells (MSCs) and their regenerative mechanisms and potentials. The review's article findings bridge fundamental biological science with translational advances, highlighting the significance of MSCs in craniofacial regenerative ...
Karim M. Fawzy El‐Sayed   +6 more
wiley   +1 more source

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