Results 61 to 70 of about 5,910 (225)

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Quantitative micro‐XRF combined with X‐ray imaging reveals correlations between Zn concentration and dentin tubule porosity across entire teeth

VIEW, Volume 7, Issue 3, June 2026.
The combination of calibrated micro‐CT and quantitative micro‐XRF measurement facilitates the correlation of density and composition in the 3D macro‐structure of teeth. Zn concentration in dentin increases by a factor of 10 toward the pulp. Incidentally, the overall density decreases, showing an association between Zn and the dentin tissue porosity ...
Ioanna Mantouvalou, Leona Johanna Bauer, Vinh‐Binh Truong, Yannick Wagener, Frank Förste, Oleksandra Marushchenko, Stephan Werner, Franco Lizzi, Frank Wieder, Timo Wolff, Birgit Kanngießer, Paul Zaslansky   +11 more
wiley   +1 more source

Cathepsin K‐Positive Cell Lineage Promotes In Situ Dentin Formation Controlled by Nociceptive Sonic Hedgehog

Advanced Science
Oral diseases affect nearly half of the global population throughout their lifetime causing pain, as estimated by the World Health Organization. Preservation of vital pulp is the therapeutic core as well as a challenge to protect natural teeth.
Ruoshi Xu, Xiaohan Zhang, Weimin Lin, Yushun Wang, Danting Zhang, Shuang Jiang, Linfeng Liu, Jiaying Wang, Xutao Luo, Xiao Zhang, Junjun Jing, Quan Yuan, Chenchen Zhou   +12 more
doaj   +1 more source

Genotypes and Phenotypes of Patients With TSPEAR‐Related Disorder: Evidence of a Predominant Dental Phenotype

American Journal of Medical Genetics Part A, Volume 200, Issue 4, Page 790-799, April 2026.
ABSTRACT TSPEAR (chr. 21q22.3) encodes a protein involved in tooth development and is predominantly expressed in the enamel knot. Biallelic loss of function variants in TSPEAR cause ectodermal dysplasia, tooth agenesis and sensorineural hearing loss. However, the role of TSPEAR in auditory processes is unclear.
Debora Vergani, Lucia Tiberi, Annarita Giliberti, Elia Dirupo, Laila Zaroili, Francesco Brancati, Michela Brena, Stefano Caraffi, Chiara De Luca, Livia Garavelli, Anna Virginia Gulino, Milena Mariani, Marzia Pollazzon, Angelo Selicorni, Samuela Landini, Ilaria Sani, Rosangela Artuso, Angela Peron   +17 more
wiley   +1 more source

FasL induces expression of Mmp13 and Osterix in bone cells

Bone Reports, 2021
Adéla Kratochvílová, Barbora Veselá, Eva Švandová, Reinhard Gruber, Eva Matalová   +4 more
doaj   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

MedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi, Shahin Ramazi, Mona Darvazi, Sepideh Yoosefi, Melika Abbasi, Shirin Farsad   +5 more
wiley   +1 more source

Fossil bears break free from inhibitory cascade constraints at least twice (Ursus minimus and Ursus deningeri) caused by dietary adaptations

Boreas, Volume 55, Issue 2, Page 503-516, April 2026.
Bears deviate from the inhibitory cascade model (ICM) during molar size evolution, with two significant deviations linked to changes in diet: Ursus minimus and Ursus deningeri. Many bears exhibit a ‘partial ICM’, highlighting the relationship between relative molar size, dietary adaptations and dental development across different species.
Anneke H. van Heteren, A. Stefanie Luft
wiley   +1 more source

Analysis of cell cycle related gene expression in Myb deficient mandible – a pilot study

Bone Reports, 2021
Sabina Stouracova, Eva Matalova, Jon Frampton, Mary Clarke, Premysl Bartos, Veronika Oralova   +5 more
doaj   +1 more source

Molecular biology of odontogenesis

Journal of Orofacial Sciences, 2011
S Chatterjee, K Boaz
doaj   +2 more sources

Sonic Hedgehog Signaling and Development of the Dentition

Journal of Developmental Biology, 2017
Sonic hedgehog (Shh) is an essential signaling peptide required for normal embryonic development. It represents a highly-conserved marker of odontogenesis amongst the toothed vertebrates.
Maisa Seppala, Gareth J. Fraser, Anahid A. Birjandi, Guilherme M. Xavier, Martyn T. Cobourne   +4 more
doaj   +1 more source