Results 71 to 80 of about 10,627 (262)

Small RNAs and tooth development: The role of microRNAs in tooth agenesis and impaction

Journal of Dental Sciences
Background/purpose: Tooth development, or odontogenesis, is a complex process in which several molecular pathways play a key role. Recently, microRNAs, a class of approximately 20-nucleotide small RNA molecules that regulate gene expression, have been ...
Agnese Giovannetti, Rosanna Guarnieri, Francesco Petrizzelli, Sara Lazzari, Gabriella Padalino, Alice Traversa, Alessandro Napoli, Roberto Di Giorgio, Antonio Pizzuti, Chiara Parisi, Tommaso Mazza, Ersilia Barbato, Viviana Caputo   +12 more
doaj   +1 more source

Mammalian dental diversity: an evolutionary template for regenerative dentistry

Frontiers in Dental Medicine, 2023
The discovery of odontogenic mechanisms essential for regenerating dental tissues and eventually developing a biomimetic artificial whole tooth for replacement is an ongoing aspiration for dental clinicians and researchers.
Tracy Popowics, Priti Mulimani
doaj   +1 more source

Immunoexpression of Wnt/β-catenin signaling pathway proteins in ameloblastoma and calcifying cystic odontogenic tumor [PDF]

, 2017
Wnt/β-catenin signaling pathway is essential for the beginning of odontogenesis and may be involved in the development and progression of some odontogenic tumors.
Armada, Luciana, Azevedo, Rebeca Souza, Dutra, Sabrina Nogueira, Pires, Fábio-Ramôa   +3 more
core   +1 more source

Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury

Cell Proliferation, EarlyView.
Retinoic acid signalling may regulate the repair processes in a tooth germ injury model using Tg(scpp5:Dendra2‐NTR) zebrafish and the nitroreductase (NTR)/metronidazole (MTZ) system. ABSTRACT Although the role of retinoic acid (RA) signalling in odontogenesis is well established, its involvement in the repair of injured tooth germs remains unclear.
Qiqi Liu, Zhenan Zhang, Weifeng Hao, Chunyan Zhou, Deqin Yang   +4 more
wiley   +1 more source

Odontogenic Effect of Icariin on the Human Dental Pulp Cells

Medicina, 2022
Background and Objectives: Human dental pulp cells (HDPCs) can be used for dentin regeneration due to its odontogenic differentiation property. Icariin can induce osteogenic differentiation of stem cells.
Guo Liu, Ying Yang, Kyung-San Min, Bin-Na Lee, Yun-Chan Hwang   +4 more
doaj   +1 more source

Endodontic approach in a replanted tooth with an immature root apex and chronic apical periodontitis: a case report [PDF]

Restorative Dentistry & Endodontics, 2020
This study describes the clinical steps taken in the treatment of a patient who had an avulsed right upper central incisor that presented with incomplete root development and chronic apical periodontitis.
Graziela Garrido Mori, Bruna Souza Andrade, Marina Bardelli Araujo   +2 more
doaj   +1 more source

Variability of systemic and oro-dental phenotype in two families with non-lethal Raine syndrome with FAM20C mutations [PDF]

, 2015
Background: Raine syndrome (RS) is a rare autosomal recessive bone dysplasia typified by osteosclerosis and dysmorphic facies due to FAM20C mutations. Initially reported as lethal in infancy, survival is possible into adulthood. We describe the molecular
A Linde, A Rejjal, AE Kan, Alan J Mighell, Ana Carolina Acevedo, AX Acosta, C Chaussain-Miller, C Gaucher, Caroline Lourenço de Lima, Chris F Inglehearn, Claire E L Smith, Clare V Logan, CM Giachelli, Colin A Johnson, D Chitayat, D Nalbant, David A Parry, E Katchburian, FK Ababneh, G Hulskamp, G Jaureguiberry, GS Kochar, HM Kingston, HO Ishikawa, J Dong, J Hao, J Raine, James A Poulter, K Al-Mane, KA Al Mane, L Ye, LI Al-Gazali, Lilian M Paula, Luiz Claudio Castro, LW Fisher, M Dure-Molla de la, M Fradin, M Koob, MA DePristo, MA Simpson, MA Simpson, P Vogel, Paulo Marcio Yamaguti, PJ Patel, Priscila Gomes Alves, PS Hart, S Takeyari, SA Shalev, SH Rafaelsen, SK Wang, SK Wang, SM Hebsgaard, T Gunes, T Mahafza, T Sreenath, V Faundes, VS Tagliabracci, X Wang, X Wang, X Wang, X Wang, Y Kinoshita   +61 more
core   +2 more sources

Effects of mineral trioxide aggregate, calcium hydroxide, biodentine and Emdogain on osteogenesis, Odontogenesis, angiogenesis and cell viability of dental pulp stem cells

BMC Oral Health, 2019
Vital pulp therapy preserves and maintains the integrity and the health of dental pulp tissue that has been injured by trauma, caries or restorative procedures.
Abdel-Rahman Youssef, Ramy Emara, M. Taher, F. Al-Allaf, Majed Almalki, Mazen A. Almasri, S. Siddiqui   +6 more
semanticscholar   +1 more source

Single‐Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis

Cell Proliferation, EarlyView.
STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Yanfei Zhu, Hongyuan Xu, Zijian Zhang, Siyuan Sun, Zihan Huang, Xin Gao, Houwen Pan, Xiangru Huang, Yuanqi Liu, Xinyu Wang, Hanbin Jia, Qinggang Dai, Lingyong Jiang   +12 more
wiley   +1 more source

Simultaneous occurence of compound odontoma and arrested root formation as developmental disturbances after maxillofacial trauma : a case report [PDF]

, 2010
Traumatic injury to a primary tooth and/or a bone fracture has the potential to damage the underlying permanent tooth germ which may disturb its development.
Aras, Hamdi, Güngörmü?, Metin, Halicio?lu, Koray, Yolcu, Ümit   +3 more
core   +1 more source