Results 51 to 60 of about 5,446 (177)
Molecular insights into the proteomic composition of porcine treated dentin matrix
Background: Human-treated dentin matrix (hTDM) has recently been studied as a natural extracellular matrix-based biomaterial for dentin pulp regeneration.
Xiya Zhang +9 more
doaj +1 more source
Understanding exosomes in regenerative dentistry
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad +2 more
wiley +1 more source
Effect of Curcumin on Odontogenic/Osteogenic Differentiation of Dental Pulp Stem Cells
Introduction: Stem cells have gained great attention in tissue engineering and curcumin is a natural phenolic product that had showed some positive effects on these cells.
Masoud Seifi +3 more
doaj +1 more source
Heterogeneity and Developmental Connections between Cell Types Inhabiting Teeth
Every tissue is composed of multiple cell types that are developmentally, evolutionary and functionally integrated into the unit we call an organ. Teeth, our organs for biting and mastication, are complex and made of many different cell types connected ...
Jan Krivanek +3 more
doaj +1 more source
Oral and dental status in children with intestinal failure: A descriptive cross‐sectional study
Abstract Background Children with intestinal failure often experience feeding difficulties and complex daily care needs, yet their oral and dental health remains underexplored. We aimed to describe oral and dental health characteristics in pediatric intestinal failure.
Anat Guz‐Mark +3 more
wiley +1 more source
Single‐Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis
STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Yanfei Zhu +12 more
wiley +1 more source
Oral diseases affect nearly half of the global population throughout their lifetime causing pain, as estimated by the World Health Organization. Preservation of vital pulp is the therapeutic core as well as a challenge to protect natural teeth.
Ruoshi Xu +12 more
doaj +1 more source
Suppression of Ciliogenesis Alleviates Cellular Senescence via AKT Signaling in Gingival Aging
In human gingival aging, aged gingival fibroblasts show increased senescence with enhanced primary cilia formation. Targeting cilia formation by knocking down IFT88 could reverse fibroblast senescence via the AKT signaling and alleviate periodontal inflammation.
Wenjun Shao +9 more
wiley +1 more source
Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury
Retinoic acid signalling may regulate the repair processes in a tooth germ injury model using Tg(scpp5:Dendra2‐NTR) zebrafish and the nitroreductase (NTR)/metronidazole (MTZ) system. ABSTRACT Although the role of retinoic acid (RA) signalling in odontogenesis is well established, its involvement in the repair of injured tooth germs remains unclear.
Qiqi Liu +4 more
wiley +1 more source
FasL induces expression of Mmp13 and Osterix in bone cells
Adéla Kratochvílová +4 more
doaj +1 more source

