Results 31 to 40 of about 5,910 (225)

Early Determination of the Periodontal Domain by the Wnt-Antagonist Frzb/Sfrp3

Frontiers in Physiology, 2017
Odontogenesis results from the continuous and reciprocal interaction between cells of the oral epithelium and cranial neural crest-derived mesenchyme. The canonical Wnt signaling pathway plays a fundamental role in mediating these interactions from the ...
Thimios A. Mitsiadis, Pierfrancesco Pagella, Claudio Cantù   +2 more
doaj   +1 more source

Bidirectional Differentiation of Human-Derived Stem Cells Induced by Biomimetic Calcium Silicate-Reinforced Gelatin Methacrylate Bioink for Odontogenic Regeneration

Biomedicines, 2021
Tooth loss or damage is a common problem affecting millions of people worldwide, and it results in significant impacts on one’s quality of life. Dental regeneration with the support of stem cell-containing scaffolds has emerged as an alternative ...
Yi-Ting Lin, Tuan-Ti Hsu, Yu-Wei Liu, Chia-Tze Kao, Tsui-Hsien Huang   +4 more
doaj   +1 more source

Integration of multimodal data in the developing tooth reveals candidate regulatory loci driving human odontogenic phenotypes

Frontiers in Dental Medicine, 2022
Human odontogenic aberrations such as abnormal tooth number and delayed tooth eruption can occur as a symptom of rare syndromes or, more commonly, as nonsyndromic phenotypes. These phenotypes can require extensive and expensive dental treatment, posing a
Emma Wentworth Winchester, Alexis Hardy, Justin Cotney, Justin Cotney   +3 more
doaj   +1 more source

Metformin carbon nanodots promote odontoblastic differentiation of dental pulp stem cells by pathway of autophagy

Frontiers in Bioengineering and Biotechnology, 2022
Human dental pulp stem cells (hDPSCs) have been a focus of pulp regeneration research because of their excellent odontogenic potential and availability.
Jinjin Lu, Jinjin Lu, Rui Li, Shilei Ni, Yuandong Xie, Yuandong Xie, Xinchen Liu, Kai Zhang, Yi Li, Yi Li   +9 more
doaj   +1 more source

Apoptotic Signaling in Mouse Odontogenesis [PDF]

OMICS: A Journal of Integrative Biology, 2012
Abstract Apoptosis is an important morphogenetic event in embryogenesis as well as during postnatal life. In the last 2 decades, apoptosis in tooth development (odontogenesis) has been investigated with gradually increasing focus on the mechanisms and signaling pathways involved.
Matalova, Eva, Svandova, Eva, Tucker, Abigail S.   +2 more
openaire   +3 more sources

Dental development in the tropical gar (Atractosteus tropicus) and the evolution of vertebrate dentitions

Developmental Dynamics, EarlyView.
Abstract Background Dentitions have diversified enormously during vertebrate evolution, involving reductions, modifications, or allocations to prey seizing and processing regions. A combination of ancient and novel features related to dental and oropharyngeal apparatuses is found in extant lineages of non‐teleost fishes, such as the gars.
Anna Pospisilova, Jan Stundl, Lenin Arias‐Rodriguez, Robert Cerny, Vladimír Soukup   +4 more
wiley   +1 more source

Oral and dental status in children with intestinal failure: A descriptive cross‐sectional study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Children with intestinal failure often experience feeding difficulties and complex daily care needs, yet their oral and dental health remains underexplored. We aimed to describe oral and dental health characteristics in pediatric intestinal failure.
Anat Guz‐Mark, Dror S. Shouval, Raanan Shamir, Esti Davidovich   +3 more
wiley   +1 more source

Small RNAs and tooth development: The role of microRNAs in tooth agenesis and impaction

Journal of Dental Sciences
Background/purpose: Tooth development, or odontogenesis, is a complex process in which several molecular pathways play a key role. Recently, microRNAs, a class of approximately 20-nucleotide small RNA molecules that regulate gene expression, have been ...
Agnese Giovannetti, Rosanna Guarnieri, Francesco Petrizzelli, Sara Lazzari, Gabriella Padalino, Alice Traversa, Alessandro Napoli, Roberto Di Giorgio, Antonio Pizzuti, Chiara Parisi, Tommaso Mazza, Ersilia Barbato, Viviana Caputo   +12 more
doaj   +1 more source

Mammalian dental diversity: an evolutionary template for regenerative dentistry

Frontiers in Dental Medicine, 2023
The discovery of odontogenic mechanisms essential for regenerating dental tissues and eventually developing a biomimetic artificial whole tooth for replacement is an ongoing aspiration for dental clinicians and researchers.
Tracy Popowics, Priti Mulimani
doaj   +1 more source

Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury

Cell Proliferation, EarlyView.
Retinoic acid signalling may regulate the repair processes in a tooth germ injury model using Tg(scpp5:Dendra2‐NTR) zebrafish and the nitroreductase (NTR)/metronidazole (MTZ) system. ABSTRACT Although the role of retinoic acid (RA) signalling in odontogenesis is well established, its involvement in the repair of injured tooth germs remains unclear.
Qiqi Liu, Zhenan Zhang, Weifeng Hao, Chunyan Zhou, Deqin Yang   +4 more
wiley   +1 more source