Results 51 to 60 of about 33,196 (280)

Whole tissue imaging of cellular boundaries at sub‐micron resolutions for deep learning cell segmentation: Applications in the analysis of epithelial bending of ectoderm

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background To understand cellular morphology, biologists have relied on traditional optical microscopy of tissues combined with tissue clearing protocols to image structures deep within tissues. Unfortunately, these protocols often struggle to retain cell boundary markers, especially at high enough resolutions necessary for precise cell ...
Sam C. P. Norris   +2 more
wiley   +1 more source

C-Jun N-terminal kinase (JNK) pathway activation is essential for dental papilla cells polarization.

open access: yesPLoS ONE, 2021
During tooth development, dental papilla cells differentiate into odontoblasts with polarized morphology and cell function. Our previous study indicated that the C-Jun N-terminal kinase (JNK) pathway regulates human dental papilla cell adhesion ...
Jiao Luo   +3 more
doaj   +1 more source

Whole Tooth Regenerative Therapy Using a Bioengineered Tooth Germ [PDF]

open access: yesCurrent Oral Health Reports, 2013
Dental disorders, including dental caries and periodontal disease, can cause fundamental problems for oral functions, such as enunciation, mastication and occlusion, as well as general health issues. Tooth regenerative therapies for tissue repair and whole tooth replacement are currently being developed as novel treatment approaches.
Kei Nakajima   +2 more
openaire   +1 more source

Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar   +11 more
wiley   +1 more source

Ontogenesis of the alveolar walls of the tooth germ according to orthopantomography [PDF]

open access: yesСаратовский научно-медицинский журнал, 2015
Objective: to identify changes of the configuration and size of the walls of the alveolar stages of ontogenesis. Materials and Methods. Orthopantomograms studied 196 children aged 5 to 12 years. We used visual and morphometric methods. Results.
Okushko M.R.   +2 more
doaj  

Fusion of a primary mandibular lateral incisor and canine: A rarity

open access: yesArchives of Medicine and Health Sciences, 2017
Fusion is a developmental anomaly of dental hard tissues characterized by the union of two adjacent teeth. It may be complete with the formation of an abnormally large tooth or incomplete with the union of crowns or roots only.
Treville Pereira
doaj   +1 more source

The Expanding Role of Gene Sequencing in Shaping Fetal Therapies: Clinical and Ethical Considerations

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT In utero interventions are transformative in addressing genetic and anatomic conditions during fetal development. Next generation sequencing enables early genetic testing, playing a pivotal role in prenatal decision‐making by supporting risk stratification, precise and timely diagnosis, which directly informs eligibility for fetal surgical and
Matthew A. Shear   +7 more
wiley   +1 more source

Tooth-bone attachment tissue is produced by cells with a mixture of odontoblastic and osteoblastic features in reptiles. [PDF]

open access: yesJ Anat
Tooth attachment in vertebrates ranges from ligament‐based anchorage in mammals to direct fusion in many reptiles. In the veiled chameleon, we identified a transient cell population—termed ankyloblasts—at the tooth‐bone interface. These cells exhibit both odontoblast‐ and osteoblast‐like features.
Šulcová M   +11 more
europepmc   +2 more sources

Kdf1 Regulates Molar Cusp Morphogenesis via the PI3K/AKT/mTOR Signalling Axis

open access: yesCell Proliferation, EarlyView.
Epithelial Kdf1 knockout disrupts molar cusp morphogenesis by promoting inner enamel epithelium proliferation and invagination via PI3K/AKT/mTOR signalling. ABSTRACT Keratinocyte differentiation factor 1 (Kdf1) reportedly plays a significant role in enamel formation.
Jiayu Wang   +9 more
wiley   +1 more source

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