Results 51 to 60 of about 437,609 (222)

Expression Levels of WNT Signaling Pathway Genes During Early Tooth Development

open access: yesOrganogenesis, 2023
It is known to all that Wnt signaling pathway plays an important role in the early development of tooth. Our previous research found that Wnt signaling pathway played crucial roles in dental development, and mutations in antagonist of Wnt signaling ...
Yuhan Song   +4 more
doaj   +1 more source

Cartilage tissue engineering on macroporous scaffolds using human tooth germ stem cells

open access: yesJournal of Tissue Engineering and Regenerative Medicine, 2017
The main objective was to study cartilage regeneration through differentiation of human tooth germ stem cells (HTGSCs) into chondrocytes on different three‐dimensional (3D) scaffolds (PCL, PLLA and PCL–PLLA).
A. C. C. Koyuncu   +5 more
semanticscholar   +1 more source

Successful Reconstruction of Tooth Germ with Cell Lines Requires Coordinated Gene Expressions from the Initiation Stage

open access: yesCells, 2012
Tooth morphogenesis is carried out by a series of reciprocal interactions between the epithelium and mesenchyme in embryonic germs. Previously clonal dental epithelial cell (epithelium of molar tooth germ (emtg)) lines were established from an embryonic ...
Yasuhiro Tomooka, Akihiko Komine
doaj   +1 more source

Epithelium-derived SCUBE3 promotes polarized odontoblastic differentiation of dental mesenchymal stem cells and pulp regeneration

open access: yesStem Cell Research & Therapy, 2023
Background Signal peptide-CUB-EGF domain-containing protein 3 (SCUBE3), a secreted multifunctional glycoprotein whose transcript expression is restricted to the tooth germ epithelium during the development of embryonic mouse teeth, has been demonstrated ...
Zijie Wang   +6 more
doaj   +1 more source

microRNA miR-34a regulates cytodifferentiation and targets multi-signaling pathways in human dental papilla cells. [PDF]

open access: yesPLoS ONE, 2012
Odontogenesis relies on the reciprocal signaling interactions between dental epithelium and neural crest-derived mesenchyme, which is regulated by several signaling pathways.
Mian Wan   +8 more
doaj   +1 more source

Dynamic expression of Mage-D1 in rat dental germs and potential role in mineralization of ectomesenchymal stem cells

open access: yesScientific Reports, 2022
Mage-D1 (MAGE family member D1) is involved in a variety of cell biological effects. Recent studies have shown that Mage-D1 is closely related to tooth development, but its specific regulatory mechanism is unclear.
Meng Li   +6 more
doaj   +1 more source

Developmental changes in primary cilia in the mouse tooth germ and oral cavity.

open access: yesBiomedical research, 2016
The primary cilium, a sensory apparatus, functions as both a chemical and mechanical sensor to receive environmental stimuli. The present study focused on the primary cilia in the epithelialmesenchymal interaction during tooth development.
Meri Hisamoto   +5 more
semanticscholar   +1 more source

Ontogenesis of the alveolar walls of the tooth germ according to orthopantomography [PDF]

open access: yesСаратовский научно-медицинский журнал, 2015
Objective: to identify changes of the configuration and size of the walls of the alveolar stages of ontogenesis. Materials and Methods. Orthopantomograms studied 196 children aged 5 to 12 years. We used visual and morphometric methods. Results.
Okushko M.R.   +2 more
doaj  

Odontodysplasia involving single tooth: A rare entity

open access: yesSRM Journal of Research in Dental Sciences, 2014
Odontodysplasia is the developmental anomaly caused due to disturbances in the ectodermal and mesodermal component of the tooth. Although it involves multiple teeth in a quadrant, the involvement of a single tooth germ is very rare. The present report is
Mahesh Ramakrishnan, Padma Menon
doaj   +1 more source

Morphometric approach to pulp fibroblast development in tooth germ. [PDF]

open access: yesBiomed Res Int, 2014
This paper builds a morphometric framework for the analysis of dental pulp fibroblast evolution during tooth development. We investigated 15 tooth germs (cases) organized, by histological criteria, in three groups corresponding to cap, early bell, and late bell stages, respectively. Each group comprised five cases. The morphometric description used the
Căruntu ID, Săvinescu SD, Amălinei C.
europepmc   +4 more sources

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