Results 71 to 80 of about 9,907 (187)

Sonic Hedgehog Signaling and Development of the Dentition

open access: yesJournal of Developmental Biology, 2017
Sonic hedgehog (Shh) is an essential signaling peptide required for normal embryonic development. It represents a highly-conserved marker of odontogenesis amongst the toothed vertebrates.
Maisa Seppala   +4 more
doaj   +1 more source

Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia

open access: yesClinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.
Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise   +5 more
wiley   +1 more source

Inverted impacted primary maxillary incisors: a case report.

open access: yesFrontiers in Dentistry, 2012
Tooth impaction rarely occurs in primary dentition. Most of the primary teeth impactions are seen in second molars. The purpose of this article is to present a 4-year-old girl with bilateral impaction of inverted primary maxillary central incisors which ...
B Seraj   +4 more
doaj  

Estudio de la proliferación celular en gérmenes dentarios humanos

open access: yesOdontoestomatología
Resumen: El objetivo de este estudio fue conocer la expresión de MCM4-5-6 en gérmenes dentarios humanos en estado de campana. Materiales y Métodos Se obtuvieron preparados histológicos de 4 maxilares fetales incluidos en parafina en el archivo de ...
Vanesa Pereira-Prado   +4 more
doaj   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

open access: yesAdvanced Materials, Volume 38, Issue 31, 2 June 2026.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen   +16 more
wiley   +1 more source

Isotretinoin: action on mice tooth germs and palate

open access: yesBrazilian Journal of Oral Sciences, 2015
Vitamin A and its derivates, acid retinoic, tretinoin and isotretinoin, are currently used in dermatological treatments. The administration of high doses of this vitamin provokes malformation in the following systems: central nervous, cardiovascular ...
Eleny Balducci Roslindo   +3 more
doaj   +1 more source

Unveiling a New Link: Cholesterol Deficiency in Smith–Lemli–Opitz and Niemann–Pick C as a Driver of Ciliopathies

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 6, Page 1179-1191, June 2026.
ABSTRACT The ciliopathies are a group of genetic disorders caused by defective function of either the primary cilia (a large number) or the motile cilia (a much smaller number). These have been defined as diseases with mutations in genes encoding individual ciliary or cilia‐associated proteins.
Robert P. Erickson   +1 more
wiley   +1 more source

Mandible-derived extracellular vesicles regulate early tooth development in miniature swine via targeting KDM2B

open access: yesInternational Journal of Oral Science
Tissue interactions play a crucial role in tooth development. Notably, extracellular vesicle-mediated interactions between the mandible and tooth germ are considered essential.
Ye Li, Meng Sun, Yi Ding, Ang Li
doaj   +1 more source

Ep-CAM (MOC-31) expression in tooth germ and ameloblastoma. [PDF]

open access: yesMed Oral Patol Oral Cir Bucal, 2022
Derderian N   +9 more
europepmc   +1 more source

High‐Grade Immature Teratoma in a 20‐Month‐Old Girl: A Rare Case With Cross‐Midline Presentation and Ovarian Torsion

open access: yesReproductive, Female and Child Health, Volume 5, Issue 2, June 2026.
ABSTRACT Background Immature ovarian teratomas are rare malignant germ cell tumours, particularly in children under 2 years old. Ovarian torsion may further obscure diagnosis by altering adnexal anatomy and radiological interpretation. Case Presentation A 20‐month‐old girl presented with persistent vomiting, abdominal distension, and poor oral intake ...
Jia Chyi Tay   +3 more
wiley   +1 more source

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