Results 61 to 70 of about 29,782 (235)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The Impact Of Talent Management On Promoting Top/Middle Managers
, 2012 This study investigates the impact of talent management by targeting its impact on Promoting of Top/Middle managers in Malaysia and the effective factors of the promotions of Top/Middle managers process. The aim of this study is to investigate the impact
Safaei, Shirin
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
, 2013 Purpose: The purpose of this thesis is to explore factors that influence the sensemaking of middle managers during strategic change, and how top managers may influence those factors by making sense of them prior to the formation of the strategy ...
Rosén, Carl +2 more
core +2 more sources
'n Model vir fasette van strategiese beplanning vir inligtingstelsels in organisasies
South African Journal of Business Management, 1990 The key to success for the information-system function in an organisation is an efficient planning system. According to Head (1967, 23) managers are classified in levels of strategic planning, management control and operational control. Managers on these
P. J.S. Bruwer
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Ho Chi Minh City Open University Journal of Science - Economics and Business Administration, 2016 A study objective is to identify key factors of QMS (Quality Management System) influencing the organizational performance in pharmaceutical factories getting GMP (Good Manufacturing Practices) certificate.
Nguyen Thuy Quynh Loan
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Choreographing Strategy: An Exploration into Middle Managers’ Embodied Interaction
, 2017 Orchestra conductors are concerned with the collective emotions of their organization. Conductors influence emotions in a visual, embodied and open way in order to create a common understanding of goals.
Gylfe, Philip
core