Results 41 to 50 of about 29,782 (235)

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

The role of middle and top managers in the strategy process

open access: yes, 2017
Since Bower’s (1970) early pioneering work in strategy process, there havebeen several decades of empirical, often survey-based or in-depth casebased, studies that examine middle managers’ involvement in strategy (e.g., Burgelman, 1983a, 1983b; Mintzberg
Yu, H., Castañer, X.
core   +1 more source

Relationship Between Organizational Culture And Intellectual Capital Among Managers Of Imam Khomeini Relief Foundation(IKRF) Deputy For Support And Health 2010

open access: yesپیاورد سلامت, 2013
Background and Aim: Investigating the effect of intellectual capital on an organization’s ongoing processes is a way of determining its weaknesses as well as appropriate strategies which help managers to make decisions. The main purpose of this study was
Amir Ashkan Nasiripour   +3 more
doaj   +2 more sources

Job satisfaction: An analysis of middle managers in the South African Police Service

open access: yesActa Commercii, 2004
The organised crime units in the South African Police Service (SAPS) have experienced major restructuring over the past two years. The impact which the restructuring would have on the middle managers was never determined This unique organisational ...
Renate Bellingan-Timmer
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

The Role of Companies in Human Capital Accumulation: Cross-Country Analysis

open access: yesForesight and STI Governance, 2015
In this article, the mechanism of human capital accumulation is explored as an example of the participation of the economically active adult population in the main forms of lifelong learning.
Natalia Bondarenko
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

The Role of Acute Care Managers in Quality of Care and Patient Safety [PDF]

open access: yes, 2013
Healthcare managers have a responsibility for the standard of their services and patient care delivered. Their work is thought to be essential in achieving and improving high quality care and patient safety.
Parand, A
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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