Results 91 to 100 of about 17,652,183 (292)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

The topic-prominence parameter [PDF]

open access: yes, 2013
This article aims to recast the properties of topic-prominent languages and their differences from subject-prominent languages as documented in the functionalist literature into the framework of the Principle-and-Parameter approach.
Xu, Liejiong
core  

Topic Intrusion for Automatic Topic Model Evaluation [PDF]

open access: yes, 2020
Topic coherence is increasingly being used to evaluate topic models and filter topics for enduser applications. Topic coherence measures how well topic words relate to each other, but offers little insight into the utility of the topics in describing the
Lau, JH, Baldwin, T, Bhatia, S
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Ideology from topic mixture statistics: inference method and example application to carbon tax public opinion

open access: yesEnvironmental Data Science
Political opposition to fiscal climate policy, such as a carbon tax, typically appeals to fiscal conservative ideology. Here, we ask to what extent public opposition to the carbon tax in Canada is, in fact, ideological in origin.
Maximilian Puelma Touzel   +1 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Apropos the topic : On topic-introducing expressions in Swedish

open access: yes, 2019
The inquiry into topicality calls for a deeper understanding of explicit "topic markers" such as apropos and concerning, which are found in many if not all the languages of Europe.
Egerland, Verner   +2 more
core   +2 more sources

ToC-RWG: Explore the Combination of Topic Model and Citation Information for Automatic Related Work Generation

open access: yesIEEE Access, 2020
Automatic related work generation is a new challenge in multi-document scientific summarization focusing on refining a related work section for a given scientific paper.
Pancheng Wang   +4 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Hierarchical neural topic modeling with manifold regularization

open access: yes, 2021
Topic models have been widely used for learning the latent explainable representation of documents, but most of the existing approaches discover topics in a flat structure.
Chen, Ziye   +13 more
core   +1 more source

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