Results 191 to 200 of about 17,652,183 (292)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Neural Topic Modelling of Short Text Survey Responses in Italian Market Research

open access: yes
reservedThis research introduces a novel model architecture designed to tackle the challenges of short-text topic modelling on corpora of open-ended survey questions.
CASARELLA, CECILIA
core  

Robust Unsupervised Topic-Based Language Model Adaptation

open access: yes, 2007
本論文的主要貢獻在於提出一個基於主題分析的語言模型調適法,這個方法主要是使用潛藏狄式配置(Latent Dirichlet Allocation, LDA)。我們使用機率式潛藏語意分析(Probabilistic Latent Semantic Analysis, PLSA)自動地把一個具有不同性質的文字語料加以聚成許多個潛藏主題,然後用這些結果當作我們LDA模型的初始化模型。我們用最後的LDA模型一句一句地建造主題式的文字語料,這些主題式語料則用來估計主題式的語言模型。當我們用語言模型調適進行N ...
Heidel, Aaron, 何恩
core  

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

open access: yesMolecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir   +9 more
wiley   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

COVID-19 and Tweets About Quitting Cigarette Smoking: Topic Model Analysis of Twitter Posts 2018-2020. [PDF]

open access: yesJMIR Infodemiology, 2022
Westmaas JL   +5 more
europepmc   +1 more source

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