Results 211 to 220 of about 814,278 (307)

Counseling Messages for Adults with Impaired Fasting Glucose in a Public Mobile Healthcare Program: A Structural Topic Model Analysis Using the IMB Framework. [PDF]

Nutrients
Jang S, Son S.
europepmc   +1 more source

Mining heterogeneous clinical notes by multi-modal latent topic model. [PDF]

PLoS One, 2021
Wen Z, Nair P, Deng CY, Lu XH, Moseley E, George N, Lindvall C, Li Y.   +7 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Evolution of traditional Chinese medicine registration review and approval policies: research based on the LDA topic model. [PDF]

Front Public Health
Lu K, Xie M, Sun W, Liu Y.
europepmc   +1 more source

Classification aware neural topic model for COVID-19 disinformation categorisation. [PDF]

PLoS One, 2021
Song X, Petrak J, Jiang Y, Singh I, Maynard D, Bontcheva K.   +5 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Determinant factors of Chief Data Officer adoption in government: A topic model and structural equation modelling approach. [PDF]

PLoS One
Zhang H, Ding H, Xiao J.
europepmc   +1 more source

Domain-specific Topic Model for Knowledge Discovery in Computational and Data-Intensive Scientific Communities. [PDF]

IEEE Trans Knowl Data Eng, 2023
Zhang Y, Calyam P, Joshi T, Nair S, Xu D.   +4 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Identifying Rare and Subtle Behaviors: A Weakly Supervised Joint Topic Model

, 2011
Gong, SG, Li, J, Timothy M. Hospedales, null Jian Li, null Shaogang Gong, null Tao Xiang, Xiang, T, Hospedales, TM   +7 more
core   +1 more source