Results 51 to 60 of about 1,611,945 (272)
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Language Models Explain Word Reading Times Better Than Empirical Predictability
Frontiers in Artificial Intelligence, 2022 Though there is a strong consensus that word length and frequency are the most important single-word features determining visual-orthographic access to the mental lexicon, there is less agreement as how to best capture syntactic and semantic factors. The
Markus J. Hofmann +4 more
doaj +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source
Service clustering method based on description context feature words and improved GSDMM model
Tongxin xuebao, 2021 To address the problem that current service clustering methods usually faced low quality of service representation vectors, a service clustering method based on description context feature words and improved GSDMM model was proposed.Firstly, a feature ...
Qiang HU +3 more
doaj
Molecular Oncology, EarlyView.Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink +6 more
wiley +1 more source
Neural Topic Modeling with Cycle-Consistent Adversarial Training [PDF]
arXiv, 2020 Advances on deep generative models have attracted significant research interest in neural topic modeling. The recently proposed Adversarial-neural Topic Model models topics with an adversarially trained generator network and employs Dirichlet prior to capture the semantic patterns in latent topics.
arxiv
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
A Survey on Opinion Mining: From Stance to Product Aspect
IEEE Access, 2019 With the prevalence of social media and online forum, opinion mining, aiming at analyzing and discovering the latent opinion in user-generated reviews on the Internet, has become a hot research topic. This survey focuses on two important subtasks in this
Rui Wang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen +13 more
wiley +1 more source