Results 141 to 150 of about 4,032,512 (303)

Topic-aware response selection for dialog systems

Natural Language Processing Journal
It is challenging for a persona-based chitchat system to return responses consistent with the dialog context and the persona of the agent. This particularly holds for a retrieval-based chitchat system that selects the most appropriate response from a set
Wei Yuan, Zongyang Ma, Aijun An, Jimmy Xiangji Huang   +3 more
doaj   +1 more source

Topic Modeling in User Item Selection.

, 2015
Topic Modeling in User Item Selection.
Bin Ju (126130), Yuntao Qian (782935), Rong Ni (259332), Chenxi Zhu (782937), Minchao Ye (782936)   +4 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Categorizing E-cigarette-related tweets using BERT topic modeling

Emerging Trends in Drugs, Addictions, and Health
Background: Social media platforms are critical channels for promoting e-cigarettes, particularly among youth, making analysis of their vast and diverse content essential for public health interventions.
D. Murthy, S. Keshari, S. Arora, Q. Yang, A. Loukas, S.J. Schwartz, M.B. Harrell, E.T. Hébert, A.V. Wilkinson   +8 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Distributed Strategies for Topic Modeling [PDF]

, 2013
Topic modeling algorithms (like Latent Dirichlet Allocation) tend to be very slow when run over large document collections. In this presentation, we discuss distributed strategies for topic modeling. We use Charm++ as our parallelization framework.
Jindal, Prateek, Kale, Laxmikant V., Hockenmaier, Julia   +2 more
core  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Analysis and application of a Topic Modeling algorithm

openQuesta tesi mira ad approfondire il topic modeling, cioè una tecnica di analisi statistica, utilizzata nell’ambito del text mining e della Knowledge Discovery Database, che permette di ricavare delle informazioni da un insieme molto vasto di dati ...
MENEGHETTI, FEDERICO
core  

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source