Results 171 to 180 of about 144,717 (245)

Advanced topic modeling with large language models: analyzing social media content from dementia caregivers. [PDF]

Innov Aging
He W, Hou B, Zheng A, Feng Y, Klein A, O'Connor K, Yang S, Shang T, Demiris G, Gonzalez-Hernandez G, Shen L.   +10 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Psychotherapist remarks' ML classifier: insights from LLM and topic modeling application. [PDF]

Front Psychiatry
Vanin A, Bolshev V, Panfilova A.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

When "Self-Harm" Means "Suicide": A Topic Modeling Study of Adolescent Online Help-Seeking for Self-Harm. [PDF]

Suicide Life Threat Behav
Lind MN, Razi A, Scholten H, George MJ, De Choudhury M, Granic I, Lal S, Wisniewski PJ, Allen NB.   +8 more
europepmc   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Financial Burden in Adults With Chronic Illness in Switzerland: A Secondary Analysis of Qualitative Interviews Using Natural Language Processing and Topic Modeling. [PDF]

JMIR Form Res
Spitale G, Seinsche J, Visscher RMS, Schöpf-Lazzarino A, Jurisic J, Germani F, Alder E, Biller Andorno N, Ribi K, Schwind B.   +9 more
europepmc   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Transformer-Based Topic Modeling: Characterizing Cannabis Product Adverse Experiences Self-Reported as Requiring Medical Attention on Reddit. [PDF]

J Med Internet Res
Mackey TK, Nali MC, Larsen MZ, Li Z, Taylor CL, Wolpert B, Trice C.   +6 more
europepmc   +1 more source