Results 241 to 250 of about 637,325 (290)
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte +13 more
wiley +1 more source
The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source
Topic model implementations, and trained models for the project datasets. Federated topic model implementations for cluster and HPC platforms. Accompanying documentation.
openaire +1 more source
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2021
Als zentrales Konstrukt der Kommunikationswissenschaft ist das Thema heute relevanter denn je. Für das Fach besitzt es als Ordnungseinheit der öffentlichen Meinung seit jeher eine besondere Bedeutung, verdankt seinen aktuellen Bedeutungszuwachs über die sozialwissenschaftliche Forschung hinaus aber erst dem Technologiewandel: Mit ihm stieg der Bedarf ...
Manika Lamba, Margam Madhusudhan
openaire +2 more sources
Als zentrales Konstrukt der Kommunikationswissenschaft ist das Thema heute relevanter denn je. Für das Fach besitzt es als Ordnungseinheit der öffentlichen Meinung seit jeher eine besondere Bedeutung, verdankt seinen aktuellen Bedeutungszuwachs über die sozialwissenschaftliche Forschung hinaus aber erst dem Technologiewandel: Mit ihm stieg der Bedarf ...
Manika Lamba, Margam Madhusudhan
openaire +2 more sources
Proceedings of the 23rd international conference on Machine learning - ICML '06, 2006
A family of probabilistic time series models is developed to analyze the time evolution of topics in large document collections. The approach is to use state space models on the natural parameters of the multinomial distributions that represent the topics.
Blei, David M., Lafferty, John D.
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A family of probabilistic time series models is developed to analyze the time evolution of topics in large document collections. The approach is to use state space models on the natural parameters of the multinomial distributions that represent the topics.
Blei, David M., Lafferty, John D.
openaire +1 more source
Neurocomputing, 2012
In this paper the problem of performing external validation of the semantic coherence of topic models is considered. The Fowlkes-Mallows index, a known clustering validation metric, is generalized for the case of overlapping partitions and multi-labeled collections, thus making it suitable for validating topic modeling algorithms.
Ramirez, E +3 more
openaire +2 more sources
In this paper the problem of performing external validation of the semantic coherence of topic models is considered. The Fowlkes-Mallows index, a known clustering validation metric, is generalized for the case of overlapping partitions and multi-labeled collections, thus making it suitable for validating topic modeling algorithms.
Ramirez, E +3 more
openaire +2 more sources